| Course title | |||||
| 免疫生物学 [Immunobiology] | |||||
| Course category | Requirement | Credit | 2 | ||
| Department | Year | 2～ | Semester | Spring | |
| Course type | Spring | Course code | 01BN2116 | ||
| Instructor(s) | |||||
| 有村 裕 [] | |||||
| Facility affiliation | Graduate School of Agriculture | Office | Email address | ||
| Course description |
| Our body is able to eliminate microbial pathogens in many cases that we have never experienced. On the other hand, our body often elicits immune responses to harmless substances such as pollen and even our tissues. What is the difference between normal and abnormal responses? We discuss the mechanism to distinguish them. |
| Expected Learning |
| (1) Able to explain different compartments and roles of immune competent cells. (2) Able to understand and explain interaction between immune cells, and a way of ultimate immune responses. (3) Able to discuss about background and solutions of unresolved problems in this fields. |
| Course schedule |
|
Week 1: Outlines and different compartments of immune cells (innate, acquired immunity). Week 2: Structure of different isotypes of antibodies. Week 3: Antigen-Antibody interaction. Maternal and transitional Antibody. Week 4: Gene rearrangement of antigen receptors. Week 5: Antigen recognition by T cells. Major histocompatibility complex (MHC). Week 6: Structure of MHC and MHC restriction. Week 7: Antigen presentation by MHC class I and II. Week 8: Allele and haplotypes of MHC genes. Week 9: Innate immunity (1) Toll-like receptors. Week 10: Innate immunity (2) Complements. Week 11: Allergy (type I). Week 12: Allergy (types II, III, IV). Week 13: Immunological tolerance and autoimmune diseases. Week 14: Thymus and T cell development. Week 15: Examination. |
| Prerequisites |
| Basic knowledge of biology and molecular biology is required. |
| Required Text(s) and Materials |
| None |
| References |
| Standard Immunology（TANIGUCHI Masaru ed. 標準免疫学、谷口克ら、医学書院）、Much Easier Immunology（KAWAMOTO Hiroshi ed. もっとよくわかる免疫学、河本宏著、羊土社）、Illustrated Immunology（KAKIUCHI Terutaka ed. 図解免疫学、垣内史堂著、オーム社）、 |
| Assessment/Grading |
| Examination（100%）attendance & small exams（0%） |
| Message from instructor(s) |
| Almost every time, small exams. Handouts should be filed and brought with you. |
| Course keywords |
| Immune cell, antibody, T cell, Antigen presenting cell, dendritic cell, innate immunity, acquired immunity, allergy, autoimmune disease |
| Office hours |
| 30 minutes after lecture at a part-time instructor’s room at 2nd floor of main building. |
| Remarks 1 |
| Lecture style: writing on the blackboard with handouts, sometimes slides. |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/28/2017 3:10:40 PM |