Course title
生命有機化学Ⅰ   [Bioorganic Chemistry Ⅰ]
Course category technology speciality courses,ets.  Requirement   Credit 2 
Department   Year 14  Semester Fall 
Course type Fall  Course code 021115
Instructor(s)
眞鍋 史乃, 櫻井 香里   [SAKURAI Kaori]
Facility affiliation Graduate School of Engineering Office   Email address

Course description
This course provides basic organic chemistry. In organic chemistry, stereochemisty is the most important issue. This course covers definition of stereochemistry, chirality, and basic reaction modes. This course also provides relationship stereochemistry and kinetics of substitution reaction and elimination reaction of alkyl halide. In addition, this course covers addition reaction to alkenes.
Expected Learning
Learners who successfully complete this course will be able to:
(1) Understand nomenclature on stereochemistry (enantiomer, diastereomer, R/S definition)
(2) Describe reaction on alkyl halide (SN1, SN2, E1, E2) in view of stereochemistry and kinetics
(3) Describe reactivity of alkene and selectivity of reaction
Course schedule
Week1: Introduction, Stereochemistry (1) (Chirality, nomenclature)
Week 2: Stereochemistry (2)(Chirality and enantiomer)
Week 3: Stereochemistry (3)(Chirality and enantiomer)
Week 4: Practice(Molecular Model, Practice)
Week 5: Stereochemistry (4)(Diastereomer and enantiomer)
Week 6: Alkyl halide (1) (Nomenclature, structure, property, and preparation)
Week 7: Alkyl halide (2) (Substituent reaction: stereochemistry and kinetics)
Week 8: Alkyl halide (2) (Elimination reaction: stereochemistry and kinetics)
Week 9: Alkene (1) (Nomenclature, structure, property, and preparation)
Week 10 Mid-semester examination
Week 11: Alkene (2) (Reactivity of alkene, addition reaction)
Week 12: Alkene (3) (Addition reaction)
Week 13: Alkene (4) (Addition reaction)
Week 14: Alkene (Reaction of carbene, Organometallic reaction)
Week 15: Examination (from Week 1 to week 14)
Prerequisites
This class is based on contents of organic chemistry in the spring semester.

Required Text(s) and Materials
Organic Chemistry (8th edition) Leroy G. Wade ISBN-13: 978-0321768414
Solutions Manual for Organic Chemistry (8th edition) Leroy G. Wade , Jan W. Simek
ISBN-13: 978-0321773890
References
Organic Chemistry, John McMurry
ISBN-13: 978-084005431
Assessment/Grading
Evaluation is based on attendance status (10%), weekly homework (10%), mid-semester examination (30%), and Examination (50%).
Distribution of evaluation (2016):S 13%; A 15%; B 21%; C 45%; D 6%
Message from instructor(s)
Biological events can be explained by organic chemistry. It is desired for you cultivate ability to explain organic chemistry based on a unified concept. We cannot take enough time for practice in the class due to time limitation. Please complement yourself with homework and exercises.
Course keywords
stereochemistry, chirality, nomenclature, nucleophilic reaction, substitution reaction, elimination reaction, alkyl halide, alkene
Office hours
After class
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
10/2/2017 9:06:23 AM