| Course title | |||||
| 分子病態制御学特論 [Advanced Molecular Pathology and Therapeutics] | |||||
| Course category | courses for the doctral program | Requirement | Credit | 2 | |
| Department | Graduate School of Bio-Applications and Systems Engineering | Year | ～ | Semester | Fall |
| Course type | Fall | Course code | 148304 | ||
| Instructor(s) | |||||
| 松田 浩珍 [MATSUDA Hiroshi] | |||||
| Facility affiliation | Faculty of Agriculture | Office | Email address | ||
| Course description |
| Students are expected to understand the developing mechanism of human and animal diseases at the gene level and molecular level, and thereby to achieve understanding of the theory pertaining to development of specific control molecules targeting on genes and molecules mainly relevant to the development of pathogenic conditions. More specifically, they will gain understanding of the flows of genes, nuclear transcription factors and signal transmitting molecules relevant to frequently occurring diseases, including allergic troubles and cancer, and signals of cell survival and propagation, and will be taught about control molecules (incuding antibodies and signal inhibitors) working on these factors as specific targets. |
| Expected Learning |
| Understanding of principles of molecular pathology and molecule-targeting therapy against cancer and allergy. |
| Course schedule |
|
1) Molecular control of life or death of molecules I 2) Activation signal of cells I 3) Classification of allergic reactions 4) Control of allergic reactions 5) Cancer genes and cancer suppressor genes 6) Propagation mechanism of cancer cells 7) Immortalization mechanism of cancer cells |
| Prerequisites |
| Required Text(s) and Materials |
| L-E C. Copstead, ed., Perspectives on Pathophysiology; Yamai no Kigen (Origins of diseases), NHK Yamai no Kigen editing group |
| References |
| Assessment/Grading |
|
The minimum total point of examination results for success is 60. ( |
| Message from instructor(s) |
| Today, molecular targeted drugs having less side effects constitute the main stream of innovative drug development. What constitutes their basis is the elucidation of the molecular mechanism of disease development. As this is a field whose understanding requires mobilization of a great deal of knowledge, students are urged to study patiently. |
| Course keywords |
| Innovative drug development, disease development function, transcription factor, lifestyle-related disease |
| Office hours |
| From 2 p.m. every Thursday |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/14/2017 5:53:06 PM |