| Course title | |||||
| 免疫生物学 [Immunobiology] | |||||
| Course category | Requirement | Credit | 2 | ||
| Department | Year | 2～ | Semester | Spring | |
| Course type | Spring | Course code | 01BN2116 | ||
| Instructor(s) | |||||
| 小柳 円 [KOYANAGI Madoka] | |||||
| Facility affiliation | Graduate School of Agriculture | Office | Email address | ||
| Course description |
| This course provides students with the mechanism how foreign material could be to recognize and eliminate in body, and also how elicits allergy and autoimmune responses to harmless substances such as pollen and even our tissues. |
| Expected Learning |
| (1) Able to explain different compartments and roles of immune competent cells. (2) Able to understand and explain interaction between immune cells, and a way of ultimate immune responses. (3) Able to discuss about background and solutions of unresolved problems in this fields. |
| Course schedule |
|
Week 1: Outlines and different compartments of immune cells (innate, acquired immunity). Week 2: Innate immunity (1) Toll-like receptors. Week 3: Innate immunity (2) Complements. Week 4: Structure of different isotypes of antibodies. Week 5: Antigen-Antibody interaction. Maternal and transitional Antibody. Week 6: Gene rearrangement of antigen receptors. Week 7: Thymus and T cell development. Week 8: Antigen recognition by T cells. Major histocompatibility complex (MHC). Week 9: Structure of MHC and MHC restriction. Week 10: Antigen presentation by MHC class I and II. Week 11: Allele and haplotypes of MHC genes. Week 12: Allergy (type I). Week 13: Allergy (types II, III, IV). Week 14: Immunological tolerance and autoimmune diseases. Week 15: Examination. |
| Prerequisites |
| Basic knowledge of biology and molecular biology is required. |
| Required Text(s) and Materials |
| None |
| References |
| Kenneth Murphy, Janeway’s Immunobiology 9rh Edition, Garland Science |
| Assessment/Grading |
| Examination（100%）attendance & small exams（0%） |
| Message from instructor(s) |
| Almost every time, small exams. Handouts should be filed and brought with you. |
| Course keywords |
| Immune cell, antibody, T cell, Antigen presenting cell, dendritic cell, innate immunity, acquired immunity, allergy, autoimmune disease |
| Office hours |
| 30 minutes after lecture at a part-time instructor’s room at 2nd floor of main building. |
| Remarks 1 |
| Lecture style: writing on the blackboard with handouts, sometimes slides. |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/27/2018 11:47:21 AM |