| Course title | |||||
| 有機合成化学 [Synthetic Organic Chemistry] | |||||
| Course category | Requirement | Credit | 2 | ||
| Department | Year | 3～ | Semester | Fall | |
| Course type | Fall | Course code | 01BN3139 | ||
| Instructor(s) | |||||
| 千葉 一裕 [CHIBA Kazuhiro] | |||||
| Facility affiliation | Center for Infectious Disease Epidemiology and Prevention Research | Office | Email address | ||
| Course description |
| The lecture is held to understand fundamental organic synthesis of biological materials such as plant and insect hormones. |
| Expected Learning |
|
To understand the basic idea about the design of the organic compound synthesis To have a basic knowledge of the carbon-carbon bond formation, functional group transformation reactions To suggest a possible synthesis method on how to synthesize organic compounds To understand the basics for stereoselective synthesis reaction To have a basic understanding of the separation and purification process of organic compounds, |
| Course schedule |
|
The significance of organic synthesis Methods of organic synthesis, key points on the experimental procedure, the carbon skeleton formation of the design, use of functional group transformation method, such as the role of the protective group It will be given with examples. Chemical synthesis of the plant hormone We will discuss on the plant hormone, and the methods of chemical synthesis that have been achieved so far,. Chemical synthesis of insect pheromones Based on the insect pheromones, we will discuss the methods of chemical synthesis and the applications. In particular, we will discuss the elucidation of absolute configuration and stereoselective chemical synthesis in detail. Chemical synthesis of insect hormone Based on the insect hormones, chemical synthesis methods and the application will be introduced. Chemical synthesis using microorganisms We will discuss the synthesis of biologically active substances using, for example, yeast reduction method, utilizing the enzyme reaction, and chemical synthesis of peptide biomolecules. We will discuss efficient chemical synthesis of peptide-related substance. Chemical synthesis of agricultural chemicals and pharmaceuticals For searching the synthesis of new pesticides and pharmaceuticals, it will be explained the process leading to the methods. |
| Prerequisites |
| Organic Chemistry 1, Organic Chemistry 2, it is desirable to have to take the organic chemistry 3. |
| Required Text(s) and Materials |
| References |
| Assessment/Grading |
| Evaluated by testing of small test and the end of the semester during school hours |
| Message from instructor(s) |
| Course keywords |
| Biologically active natural products chemistry, organic chemistry, synthetic organic chemistry, physiologically active substances |
| Office hours |
| Every Tuesday 12:00 to 13:00 |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 6/11/2018 2:45:50 PM |