| Course title | |||||
| 生命物理化学Ⅰ [Biophysical Chemistry Ⅰ] | |||||
| Course category | technology speciality courses,ets. | Requirement | Credit | 2 | |
| Department | Year | 2～4 | Semester | Spring | |
| Course type | Spring | Course code | 022104 | ||
| Instructor(s) | |||||
| 中村 暢文 [NAKAMURA Nobufumi] | |||||
| Facility affiliation | Faculty of Engineering | Office | Email address | ||
| Course description |
| Students will learn about physical chemistry becoming basic in biotechnology in this class. This class covers chemical equilibrium and electron transfer based on the thermodynamics and spectroscopies based on the quantum mechanics. |
| Expected Learning |
|
Students who successfully complete this class will be able to: 1) Discuss chemical equilibrium, phenomena responsible for life, and biopolymer based on thermodynamics. 2) Recognize basic quantum mechanics and understand spectroscopies which is used for observation of biomolecules. |
| Course schedule |
|
Week 1: Orientation of this class. Reviewing thermodynamics. Week 2: Phase equilibria 1 (Chapter 3) Learning phase, phase transition, and phase diagram. Week 3: Phase equilibria 2 (Chapter 3) Learning ideal solutions, Raoult’s law, ideal-dilute solutions, and Henry’s law. Week 4: Phase equilibria 3 (Chapter 3) Understanding phase transitions in biopolymers and of biological membranes and chemical potential. Week 5: Phase equilibria 4 (Chapter 3) Understanding the real solutions, activity, and colligative properties. Week 6: Chemical equilibrium 1 (Chapter 4) Learning the reaction Gibbs energy, chemical equilibrium, the equilibrium constant. Week 7: Chemical equilibrium 2 (Chapter 4) Understanding Le Chatelier’s principle and bioenergetics. Week 8: Chemical equilibrium 3 (Chapter 4) Understanding acids and bases, proton transfer equilibria, and buffer solutions. Week 9: Midterm examination Week 10: Some comments about the midterm examination Week 11: Thermodynamics of ion and electron transport 1 (Chapter 5) Understanding transport of ions across biological membranes and redox reactions. Week 12: Thermodynamics of ion and electron transport 2 (Chapter 5) Understanding standard potentials and electron transfer in bioenergetics. Week 13: Biochemical spectroscopy 1 (Chapter 12) Reviewing quantum mechanics. Learning vibrational spectroscopies (IR and Raman). Week 14: Biochemical spectroscopy 2 (Chapter 12) Learning ultraviolet and visible absorption spectroscopy and fluorescence spectroscopy. Week 15: Final examination |
| Prerequisites |
| Students entering this class are assumed to have had “Thermodynamics” and “Basic quantum mechanics”. This class leads to “Biophysical chemistry II” and “Bio-related electronics”. |
| Required Text(s) and Materials |
| Peter Atkins and Julio de Paula, Physical chemistry for the life sciences 2nd Edition, Oxford University Press 2011. |
| References |
|
1) Donald A. McQuarrie and John D. Simon, Physical chemistry -a molecular approach-, University Science Books 1997. 2) Peter Atkins and Julio de Paula, Atkins' Physical chemistry 9th Edition, Oxford University Press 2010. 3) Hans Kuhn and Horst-Dieter Feorsterling, Principles of physical chemistry, Wiley 1999. |
| Assessment/Grading |
| Grades will be assigned based on students' performance on examination, quizzes, and reports. Midterm examination; 40% and Final examination; 60%. Quizzes and reports will cause +alpha. |
| Message from instructor(s) |
| Let's learn about principles of life and physicochemical methods to observe life with pleasure! |
| Course keywords |
| Thermodynamics, Quantum mechanics, Chemical equilibrium, Electron transfer, Bioenergetics, Spectroscopy |
| Office hours |
| 16:00-17:00 Friday; Room 307, 3rd floor, 12th Building, Koganei Campus |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| English |
| Last update |
| 4/10/2018 1:57:54 PM |