| Course title | |||||
| 有機化学Ⅲ [Organic ChemistryⅢ] | |||||
| Course category | technology speciality courses,ets. | Requirement | Credit | 2 | |
| Department | Year | 2～4 | Semester | Spring | |
| Course type | Spring | Course code | 022308 | ||
| Instructor(s) | |||||
| 中野 幸司 [NAKANO Koji] | |||||
| Facility affiliation | Faculty of Engineering | Office | Email address | ||
| Course description |
| Organic chemistry is basis for development of organic and polymer materials, while it requires an integrated approach that combines design, synthesis, and analysis of new materials and evaluation of their functionality. This course provides basic knowledge and concept in organic chemistry systematically, following Organic Chemistry I and II. The topics covered in this course are chemistry of alkynes and allylic and aromatic compounds with carbon-carbon multiple bond(s) and carbonyl compound such as aldehydes and ketones. |
| Expected Learning |
| Aromatic compounds and carbonyl compounds covered in this course is an important class of compounds in synthetic organic chemistry. Students will acquire the knowledge and skills to design the synthetic route to simple organic molecules by understanding a various type of carbon-carbon bond forming reactions and functional-group transformation and reaction mechanisms of them. |
| Course schedule |
|
This course will cover Chapters 13~18 in the text. The approximate order of topics to be covered is given below. [Weeks 1 and 2] Orientation Chapter 13 Alkynes: Properties and spectroscopy of alkynes, Preparation of alkynes, Reaction of alkynes (alkynyl anions, reduction and electrophilic addition of alkynes) [Weeks 3 and 4] Chapter 14: Delocalized Pi system: Properties and spectroscopy of allyl and conjugated-diene compounds, Reaction of allylic and diene compounds (substitution via radical mechanism, nucleophilic substitution, allylation, Diels-Alder reaction, electrocyclic reaction) [Weeks 5, 6, and 7] Benzene and Aromaticity: Aromaticity, Huckel’s rule, Properties and spectroscopy of aromatic compounds, electrophilic aromatic substitution, Friedel-Crafts reaction) [Week 8] Midterm exam [Weeks 9 and 10] Chapter 16 Electrophilic attack on derivatives of benzene: Effect of substituents on electrophilic aromatic substitution [Weeks 11, ans 12] The lectures will be given on the basis that you have taken Organic Chemistry I and II and understood the course contents. Chapter 17 Aldehydes and Ketones: Properties and spectroscopy of aldehydes and ketones, Preparation of aldehydes and ketones, reaction of aldehydes and ketones (acetalization, conversion to imines and enamines, oxidation, reduction, Wittig reaction) [Weeks 13 and 14] Chapter 18 Enols, Enolates, and the Aldol condensation: keto-enol tautomerization, reaction on alpha-carbon, aldol condensation, Michael addition, Robinson annulation) [Week 15] Final exam |
| Prerequisites |
| Required Text(s) and Materials |
|
Organic Chemistry: Structure and Function 7th edition Peter Vollhardt, Neil E. Schore, ISBN: 978-1464120275 |
| References |
| The lectures will be given on the basis that you have taken Organic Chemistry I and II and understood the course contents (Chapters 1-12 in the textbook). |
| Assessment/Grading |
|
There will be midterm exam (worth 45% of the grade) and final exam (worth 45% of the grade). Homework assignments will together count 10% of the grade. |
| Message from instructor(s) |
| I strongly recommend you to read the text in advance before you attend the class since the text is written in English. You should download, print out, and bring the handouts which will be put on Moodle. |
| Course keywords |
| Office hours |
| One hour after each lecture. Please try to make an appointment (e-mail: k_nakano@cc.tuat.ac.jp; Tel: 042-388-7162) if you are unable to attend the scheduled office hours. |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 4/4/2018 10:06:00 AM |