| Course title | |||||
| 生物化学Ⅱ [Bio Chemistry Ⅱ] | |||||
| Course category | technology speciality courses,ets. | Requirement | Credit | 2 | |
| Department | Year | 3～4 | Semester | Fall | |
| Course type | Fall | Course code | 023217 | ||
| Instructor(s) | |||||
| 岩井 伯隆 [IWAI Noritaka] | |||||
| Facility affiliation | Graduate School of Engineering | Office | Email address | ||
| Course description |
| Biological Chemistry ( Biochemistry ) focuses life from the point of view of chemistry. It is a basic science to understand life. Whole life ( Animals, Plants, Microbes ) consists of cell(s). The cell activities are important to maintain life, those contain taking nutrition, excretion of wastes, intracellular metabolism and cell-cell communication. Those phenomena are able to understand by chemistry. In this lecture, the metabolic pathways of four kinds of basic contents in the cell are learned. You can understand the way of gaining the energy and the nutrition. |
| Expected Learning |
|
Learners who successfully complete this lecture will be able to 1.Know the basic of metabolism and functions of enzymes 2.Understand and lead the equation of enzyme kinetics by yourself 3.Notice the roll of each metabolic pathway and those networks Review the lecture as soon as possible is important to understand this subject rather than preparation. |
| Course schedule |
|
1st lecture ( Oct. 1 ): Guidance about this lecture, short examination for review of the first semester 2nd lecture ( Oct. 8 ): Membrane transport ( Passive-mediated transport : ionophores, porins & ion channels, Active transport : ATP-dependent transporters & secondary active-transporters ) 3rd lecture ( Oct. 15 ): General properties of Enzymes ( important respects, specificity, types of cofactors, reaction coordinate ) 4th lecture ( Oct. 22 ): Enzyme kinetics I ( Michaelis-Menten equation, assumption of steady state, Lineweaver-Burk(double-reciprocal) plot, catalytic efficiency, turnover number ) 5th lecture ( Oct. 29 ): Enzyme kinetics II ( Enzyme inhibition : competitive inhibition, uncompetitive inhibition & mixed(noncompetitive) inhibition, Control of enzyme activity : allosteric effectors & covalent modification ) 6th lecture ( Nov. 5 ): Metabolism ( rolls of high-energy compounds & electron carriers ), Glycolysis ( overview ) 7th lecture ( Nov. 12 ): Citric acid cycle ( overview, cataplerotic reactions, anaplerotic reactions ) 8th lecture ( Nov. 19 ): Midsemester examination 9th lecture ( Nov. 26 ): Electron transport and Oxidative phosphorylation ( the mitochondrion, overview of electron transport chain, energy coupling, chemiosomotic theory ) 10th lecture ( Dec. 3 ): Pentose phosphate pathway ( overview, two aims of this pathway ) 11th lecture ( Dec. 10 ): Photosynthesis I ( the chloroplast, the light reactions ) 12th lecture ( Dec. 17 ): Photosynthesis II ( the dark reactions(Calvin cycle), C4 cycle ) 13th lecture ( Jan. 7 ): Lipid metabolism I ( lipid digestion, absorption and transport in human, fatty acid oxidation ) 14th lecture ( Jan. 21 ): Lipid metabolism II ( fatty acid biosynthesis ) 15th lecture ( Jan. 28 ): Final exams This program is tentative plan. Modification is possible. |
| Prerequisites |
| Students entering this class are assumed to have had not only undergraduate chemistry, physics and math, but also Biological Chemistry I. |
| Required Text(s) and Materials |
|
D. Vote, J. Vote, C. Pratt, Fundamentals of Biochemistry -Life at the Molecular Level- 3rd edition, Wiley Japanese translation edition by Tokyo Kagaku Dozin Co., Ltd. |
| References |
|
D. Vote, J. Vote, Biochemistry 3rd edition, Wiley Japanese translation edition by Tokyo Kagaku Dozin Co., Ltd. |
| Assessment/Grading |
|
Midsemester examination ( 45% ), Final exams ( 45% ), Attendance ( 10% ) It is required to take final exams that two thirds or more of the number of attendance. |
| Message from instructor(s) |
| The knowledge mastered from this lecture, is concerned with your life itself. You can see the words ,those learned from this class, in some drinks, some foods and so forth. Impress and excite the beauty and delicacy of life at the molecular level! |
| Course keywords |
| Enzymes, Metabolism |
| Office hours |
| If you have any questions about this class, please ask me after the lecture soon. Because my sojourn time in campus is very short. |
| Remarks 1 |
| Remarks 2 |
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The results distribution in the past three yares are as below H29 (2017) S 29%, A 57%, B 10%, C 2%, D 2% H28 (2016) S 25%, A 31%, B 39%, C 4%, D 2% H27 (2015) S 31%, A 34%, B 22%, C 11%, D 2% |
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| Last update |
| 3/27/2018 2:25:18 PM |