Course title
環境老年学特別演習Ⅰ   [Special Seminar on Environmental Gerontology Ⅰ]
Course category thesis research and other related studies  Requirement   Credit 2 
Department   Year 1  Semester YearLong 
Course type YearLong  Course code 05ML5505
Instructor(s)
重本 和宏   [SHIGEMOTO Kazuhiro]
Facility affiliation Graduate School of Agriculture Office   Email address

Course description
Epidemiological findings suggest that the pathogenesis and mortality rates of many age-related diseases are associated with sarcopenia, a condition defined as age-associated muscle weakening and atrophy. Skeletal muscle plays important roles beyond bodily movement, including modulating metabolic homeostasis in response to environmental changes. Our aim, in this course, is to study the current progress in molecular mechanisms of age-related muscle atrophy, find the problems to be solved, and discuss the solutions for the prevention of sarcopenia.

Central nervous system is the basis for biological man to be human being. Memory, especially, plays fundamental roles for other higher cognitive functions to determine one’s personality and behaviors. The impairment of memory due to dementia and other diseases influence significantly over life of patients and family. In this advanced seminar, we aim to obtain basic knowledge on neuroscience through the intensive discuss the general neuroscience and particular emphasis on memory mechanisms.
Expected Learning
You can discuss on
1)What is the mechanisms of muscle atrophy?
2) How is our motor system maintained?
3) Discuss on the molecular mechanisms of metabolic homeostasis regulated by muscles.

1) To understand basic terms and definitions in neuroscience
2) To be familiar with naming of brain areas and their roles
3) To obtain the structure of nervous cells and the communications between them
4) To get ideas of intracellular signaling systems to control nervous system
5) To acquire the memory mechanisms other than mammalians

Course schedule
Intensive reading of published papers, reviews, books
Discussion on our current research
Presentation of own research
Prerequisites
Students who are interested in Sarcopenia.
Basic knowledge on the mammalian cell biology.
Pre-acquisition of any one of following subject;
cell biology, physiology, molecular biology, biochemistry or pharmacology.
Required Text(s) and Materials
Published scientific papers and reviews
Memory (by Eric Kandel)
References
“biology of aging” by Roger B. McDonald, Garland Science (NEW YORK AND LONDON)
Assessment/Grading
A report on the subject.
Message from instructor(s)
Not only Japan, but also other Asian countries including Korea and China, and European countries will soon have the same problems arisen from the super aging society. Let’s discuss “Sarcopenia”!

You will learn the basic mechanisms for biological man to be human being through the neuroscience.
Course keywords
Office hours
9:00-17:00
Remarks 1
Remarks 2
Related URL
http://www.tmghig.jp/J_TMIG/kenkyu/team/undokiigaku.html  http://www2.tmig.or.jp/Mn_B/English/index.html
Lecture Language
Japanese
Language Subject
Last update
6/12/2018 3:30:30 PM