| Course title | |||||
| 生物生産科学フロンティア講義Ⅰ [Special Lectures on Frontier of Biological Production Ⅰ] | |||||
| Course category | Requirement | Credit | 0.5 | ||
| Department | Year | 1～ | Semester | Spring | |
| Course type | Spring | Course code | 05MP5102 | ||
| Instructor(s) | |||||
| 藤本 浩文, 天竺桂 弘子 [TABUNOKI Hiroko] | |||||
| Facility affiliation | Faculty of Agriculture | Office | Email address | ||
| Course description |
|
Various types of modifications are continually generated on DNA by exposure to ionizing radiation or by various chemical species resulting from endogenous metabolism. Those modifications are inferred to increase the frequency of mutations if they are left unrepaired, and, finally, this process may induce apoptosis or initiate onset of cancer. The lecture outlines DNA lesions, especially those caused by irradiation and how repair enzymes recognize and repair these DNA lesions, and introduces how to study properties of those biomolecules by combining an experimental methods and a molecular simulation technique. |
| Expected Learning |
| To understand DNA lesions, especially those caused by irradiation, how repair enzymes recognize and repair these lesions, and how to study properties of those biomolecules by an experimental methods and a molecular simulation technique |
| Course schedule |
|
1) ionizing radiation and its biological effects 2) DNA damage 3) repair mechanism of DNA damage 4) molecular simulation technique |
| Prerequisites |
| None |
| Required Text(s) and Materials |
| None |
| References |
| Introduced in the lecture |
| Assessment/Grading |
| Report:70%, Attendance:30% |
| Message from instructor(s) |
| Course keywords |
| DNA damage and repair; ionizing radiation; molecular simulation technique |
| Office hours |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/26/2018 3:07:03 PM |