Course title
有機反応化学特論   [Advanced Organic Reaction]
Course category courses for master's programs  Requirement   Credit 2 
Department   Year   Semester Spring 
Course type Spring  Course code 1060201
Instructor(s)
森 啓二, 平野 雅文   [MORI Keiji, HIRANO Masafumi]
Facility affiliation Faculty of Engineering Office   Email address

Course description
All organic compounds possesses three dimentional structure because main unit, carbon, can have four substituents around it. Since the properties on molecule is dramatically changed by the three dimentional structure, the stereoselective synthesis of organic acrchitecture is major topic in synthetic organic chemistry.
In this lecture, I want to explain the details about stereocontrolled synthesis of various important class of organic molecules, and the way of thinking of the reaction mechanism using curved arrow.
Expected Learning
Understanding the stereoselective reaction, which is indispensable knowledge in modern synthetic organic synthesis
Course schedule
1st Lecture: introduction
2nd Lecture: Fundamental information on asymmetric synthesis
3rd Lecture: DIels-Alder reaction 1
4th Lecture: DIels-Alder reaction 2
5th Lecture: Aldol reaction 1
6th Lecture: Aldol reaction 2
7th Lecture: Midterm test
8th Lecture: Stereoselective synthesis of olefins 1
9th Lecture: Stereoselective synthesis of olefins 1
10th Lecture: Pericyclic reaction 1
11th Lecture: Pericyclic reaction 2
12th Lecture: Asymmetric synthesis involving kinetic resolution 1
13th Lecture: Asymmetric synthesis involving kinetic resolution 2
14th Lecture: Method for controlling of various special asymmetric information
15th Lecture: Final test (The contents of all lectures are on the test)
Prerequisites
Although teacher consider about students who are not familiar with organic chemistry, the fundamental knowledge, which are taught in bachelor degree, are indispensable to understand the contents.
Required Text(s) and Materials
nothing
References
Organic Chemistry for lecture in graduate course edited by R. Noyorei, M. Shibasaki, K. Suzuki, K. Tamao, K. Nakasuji, K. Narasaka, Tokyo Kagaku Dojin Ltd. Co.
Assessment/Grading
The method of a scholastic evaluation: Consider it as attendance + homework (50%), a midterm exam (25%), and a term-end examination (25%), and judge in these sum totals.
Message from instructor(s)
Become a expert on rationalizing the stereochemistry, which is weak point for most of the student
Course keywords
stereoselective synthesis, catalytic reaction, asymmetric reaction
Office hours
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
3/23/2018 7:32:53 PM