Course title
昆虫生理生化学特論   [Advanced Insect Physiology and Biochemistry]
Course category   Requirement   Credit 0.5 
Department   Year   Semester Fall 
Course type Fall  Course code 96133
Instructor(s)
天竺桂 弘子   [TABUNOKI Hiroko]
Facility affiliation Faculty of Agriculture Office   Email address

Course description
“Elucidation of the molecular mechanisms involved in oxidative stress tolerance that are conserved among species.”
Insects are exposed to a wide range of environmental stressors. These stressors cause the generation of reactive oxygen species (ROS) in the insect’s body. ROS are the intermediates of oxygen reduction processes such as respiration redox reactions, chemical metabolism, and energy production. Under normal conditions, ROS can be useful for the body, as they serve as secondary messengers. However, with excessive exposure to stressors, the production of additional ROS leads to oxidative stress. Environmental conditions can have physiological effects on insect development, aging, growth, longevity, survival, and reproduction. However, insects can rapidly adapt to environmental changes through physiological responses.
If we can clarify how insects is adapted to the stress factors and which molecules they are using, we can elucidate a part of the mechanism of insect environmental adaptation strategy.
While, they are completely different organisms between insects and human evolution, but there are many genes that are very similar in humans and insects. Also, important physiological processes are conserved between human and insects. In this lecture, I will review the outline of our latest research for the mechanism of stress response in the insects and introduce the examples of its application. Finally, we discuss how insects can be used for human studies in the future.
Expected Learning
Understanding the differences between physiological systems in insects and humans, and students will be able to discuss insect usage.
Course schedule
(1)Automatically gene functional annotation in the insects.
(2)Comparison of gene function of insects with the human.
(3)Construction of human disease model using insects.
Prerequisites
Required Text(s) and Materials
To be announced in the lectures.
References
To be announced in the lectures.
Assessment/Grading
Attendance 30%, Report 70%
Message from instructor(s)
I’d like to introduce insect physiology and biochemistry, whose topics are interested in doctoral students with different fields of specialization. Understanding the differences between insects and humans are useful for not only agricultural industry but also medical research.
Course keywords
Office hours
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
3/26/2018 3:15:54 PM