Course title
生物制御化学特論   [Advanced Bioregulation Chemistry]
Course category   Requirement   Credit 0.5 
Department   Year   Semester Spring 
Course type Spring  Course code 96135
Instructor(s)
戸嶋 浩明(茨)   [TOSHIMA Hiroaki]
Facility affiliation United Graduate School Agricultural Science Office   Email address

Course description
“Chemical Synthesis of Biologically Active Substances and their Probes”
Biological phenomena are regulated by the interaction between low-molecular-weight biologically
active substances and biopolymers (enzyme, protein, DNA, RNA ). To study the mechanism of biological
phenomena at the molecular level, synthesizing low-molecular-weight biologically active substances and
their probes with precision methods are required. Basic and new methodologies in the chemical synthesis
of required compounds and recent developments in chemical biology are reviewed. Some examples are
described in this lecture.
Expected Learning
To understand the outline of basic and new methodologies in the chemical synthesis of required
compounds and recent developments in chemical biology.
Course schedule
1. Basic and new methodologies in the chemical synthesis and chemical biology
2. Synthesis of coronatine and jasmonate signaling probes
3. Synthesis of some probes for diterpene biosynthetic study
4 Synthesis of flower-inducing substance, KODA, its derivatives and probes
Prerequisites
Required Text(s) and Materials
Handouts will be provided in class.
References
To be announced in the lectures.
Assessment/Grading
Message from instructor(s)
I hope you will understand the importance of chemical synthesis of
biologically active substances in the study of biological phenomena.
Course keywords
Office hours
Remarks 1
Remarks 2
Related URL
Lecture Language
Language Subject
Last update
3/23/2018 5:15:47 PM