Course title
生化学Ⅰ   [Biochemistry I]
Course category   Requirement   Credit 2 
Department   Year 1  Semester 1st 
Course type 1st  Course code 01bn1003
Instructor(s)
西河 淳, 殿塚 隆史   [NISHIKAWA Atsushi, TONOZUKA Takashi]
Facility affiliation Faculty of Agriculture Office 3-211  Email address

Course description
[Course objective] In this course, Biochemistry I, the students learn the structures, chemical and physical properties and interactions of biomolecules such as amino acids, proteins, carbohydrates, lipids, and their complexes.

[Course synopsis] Biochemistry is the investigation of the molecular basis of life. The students should understand the chemical and physical properties of biological molecules influence their function as the biochemical baseline knowledge.

Expected Learning
- Understanding the structures and functions of essential molecules that are composed of bioorganisms
- Understanding the physiological roles of biomolecules

Corresponding criteria in the Diploma Policy: (B)
Please refer to the curriculum map at the following URL:
https://www.tuat.ac.jp/campuslife_career/campuslife/policy/.
Course schedule
Structure and function of biomolecules (Atsushi Nishikawa)
1) Introduction - the major objective of biochemistry
2) Amino acid and protein - the structures, properties and analytical methods of amino acids
3) Amino acid and protein - the structures, properties and analytical methods of proteins
4) Amino acid and protein - the post-translational modifications and localizations of proteins
5) Enzyme - properties of enzymes
6) Enzyme - enzyme kinetics
7) Carbohydrate - the structures, properties and analytical methods of carbohydrates
8) Carbohydrate - the structures and functions of polysaccharides
9) Biological polymer - the structures and functions of biological molecules
10) Review / examination

Glycolysis and related metabolic pathways (Takashi Tonozuka)
11) Metabolism overview and bioenergetics
12) Glycolysis
13) Pentose phosphate pathway
14) Gluconeogenesis
15) Regulation of glycolysis and related pathways / examination
Prerequisites
Students need to preview and review for an amount of time as indicated in the student guidelines of TUAT, in addition to the attendance of lecture.
Required Text(s) and Materials
Biochemistry (T. McKee and J.R. McKee, McGRAW-HILL, a Japanese edition is from Kagaku Dojin). Biochemistry (L. Stryer et al. W.H.Freeman & Co Ltd, a Japanese edition is from Tokyo Kagaku Dojin). etc.
References
Stryer “Biochemistry”; Voet “Biochemistry”, etc.
Assessment/Grading
Nishikawa: 2/3 of the total: performance in lecture (including assignment) 10 %, examination 90%
Tonozuka: 1/3 of the total: performance in lecture 10%, examination 90%
Message from instructor(s)
Students are expected to learn self-discipline and behave appropriately.
Course keywords
Amino acid, Protein, Carbohydrate, Biomolecule, Enzyme, Enzyme kinetics, Glycolysis
Office hours
Friday 13:00 - 17:00, we will be in my office during these time. If you have a question or a concern, you can visit my office anytime. If you want to meet with me without fail, please make an appointment by e-mail.
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
7/2/2019 8:38:20 PM