Course title
生体有機化学   [Bioorganic Chemistry]
Course category	technology speciality courses,ets.	Requirement		Credit	2
Department		Year	2～4	Semester	3rd
Course type	3rd	Course code	022219
Instructor(s)
齊藤 亜紀夫   [SAITO Akio]
Facility affiliation	Faculty of Engineering	Office		Email address

Course description

This course can be recognized as the application after finishing studies of organic chemistry I to III. Students study proteins and nucleotides, lipids, sugars during this lecture, and for understanding these subjects especially on metabolic pathways, combination of knowledge about such carbonyl compounds as amides, esters, aldehydes and amines and phosphonic acids are highly required. Thus, it is desirable for students to confirm issues already studied in previous lectures after having explanations at the class. In this course, lectures are given using Microsoft PowerPoint. In each lecture, handouts are distributed.

Expected Learning

1. To understand properties, reactions and synthetic methods of amines. 2. To understand properties, reactions and synthetic methods of bio-related substances (sugars, peptides, lipids, nucleic acids). 3. To understand metabolic pathways from the viewpoint of the organic chemistry. Corresponding criteria in the Diploma Policy: See the Curriculum maps.

Course schedule

1st lecture: Guidance of this course / Chapter 24-Amine Part 1: properties of amines. 2nd lecture: Chapter 24-Amine Part 2: reactions and synthetic methods of amines. 3rd lecture: Chapter 24-Amine Part 3: heterocyclic amines. / Chapter 25-Sugar Part 1: classifications and stereochemistries of sugars. 4th lecture: Chapter 25-Sugar Part 2: structures and reactions of sugars. 5th lecture: Chapter 26-Amino Acid/Peptide/Protein Part 1: amino acids. 6th lecture: Chapter 26-Amino Acid/Peptide/Protein Part 2: peptides and proteins 7th lecture: Summary of 1st-6th lectures, midterm examination 8th lecture: Chapter 27-Lipid Part 1: oils and fats, soaps, phosphatides, eicosanoids 9th lecture: Chapter 27-Lipid Part 2: terpenoids and steroids 10th lecture: Chapter 28-Nucleic acid 11th lecture: Chapter 29-Organic chemistry for the metabolic pathway Part 1: Outline of metabolic pathways 12th lecture: Chapter 29-Organic chemistry for the metabolic pathway Part 2: metabolic pathways of lipids and sugars 13th lecture: Chapter 29-Organic chemistry for the metabolic pathway Part 3: citric acid cycle and metabolic pathways of lipids and proteins 14th lecture: total reviews 15th lecture: Summary of 1st-14th lectures, term examination

Prerequisites

This course is classified in technology speciality courses and provides one of the department-recommended organic chemistry subjects. Require preparation and review hours recommended by this university along with school hours (30 hours). Do preparation and review using textbooks and handouts. It is desirable for students to have already studied about organic chemistry I to III.

Required Text(s) and Materials

The textbook of Organic Chemistry by McMurry (8th Edition) is used for this lecture, and the corresponding study guide and student solution manual would be useful for students' self study.

References

General biochemical textbooks: e.g., Voet’s basic biochemistry

Assessment/Grading

Grades are given based 50 % on the score of midterm examination and 50% on the score of midterm examination.

Message from instructor(s)

Since this course supplies advanced contents of organic chemistry I to III, students should check the uncomprehended contents in organic chemistry I to III

Course keywords

sugars, peptides, lipids, nucleic acids

Office hours

Whenever I am in my office, I take questions.

Remarks 1

Grade points distribution in 2015: S 10%, A 20%, B 31%, C 27%, D 12% Grade points distribution in 2016: S 6%, A 24%, B 24%, C 35%, D 12% Grade points distribution in 2017: S 6%, A 23%, B 19%, C 40%, D 10% Grade points distribution in 2018: S 9%, A 23%, B 26%, C 28%, D 15%

Remarks 2

Related URL

Lecture Language

Japanese

Language Subject

Last update

3/15/2019 2:38:00 PM