Course title
生理生化学特論Ⅱ   [Advanced Physiological and Biological Chemistry Ⅱ]
Course category specialized field courses  Requirement   Credit 2 
Department   Year 2  Semester 1st 
Course type 1st  Course code 05ML5302
Instructor(s)
殿塚 隆史   [TONOZUKA Takashi]
Facility affiliation Faculty of Agriculture Office afjgxte/L1151  Email address

Course description
[Objective] The purpose of this lecture is to provide students with the knowledge needed to understand the latest outcomes of the field of physiological and biological chemistry.

[Synopsis] This lecture introduces the knowledge of carbohydrate acting enzymes, Anti-cancer drugs, bioactive natural compounds, animal cell membrane, glycoprotein sugar chain, etc.
Expected Learning
- Understanding the structure and function of carbohydrate actiing enzymes
- Understanding the physiological and biochemical aspects of cancer
- Understanding the discovery and development of bioactive natural compounds
- Understanding the animal cell membrane
- Understanding the physiological function of glycoprotein sugar chain

Corresponding criteria in the Diploma Policy: (A)
Please refer to the curriculum map at the following URL:
https://www.tuat.ac.jp/campuslife_career/campuslife/policy/.
Course schedule
(Takashi Tonozuka)
1) Structure and function of carbohydrate actiing enzymes
2) How to write a scientific paper
3) How to make a presentation

(Eriko Suzuki)
4) Latest diagnostic technology for cancer and therapeutic approaches in cancer treatment
5) (1) Development of anti-cancer drugs (2)The absorption, distribution, metabolism and excretion of drugs
6) (1)The signal transduction involved in the tumor malignancy (2) Recent advances in cancer stem cell research

(Keiji Hasumi)
7) Discovery and development of bioactive natural compounds (1) An introduction.
8) Discovery and development of bioactive natural compounds (2) Examples of commercialized drugs.
9) Discovery and development of bioactive natural compounds (3) Perspective and discussion.

(Yutaka Miura)
10) Cell membrane is important for the functions of animal cells. The structure and physiological significance of cell membrane will be lectured.
11) The recent concept for animal cell membrane structure will be lectured, focusing the structures and functions of lipid microdomains in cell membrane.
12) The effects of dietary membrane lipids on cell functions will be lectured.

(Atsushi Nishikawa)
13) Physiological function of glycoprotein sugar chain (basic)
14) Physiological function of glycoprotein sugar chain (advanced)
15) Physiological function of glycoprotein sugar chain (future)
Prerequisites
Students belonging to the course of physiological and bioligical chemistry must take this lecture.
Students need to preview and review for an amount of time as indicated in the student guidelines of TUAT, in addition to the attendance of lecture.
Required Text(s) and Materials
Handouts will be provided if needed.
References
Harper's Illustrated Biochemistry, etc.
Assessment/Grading
Performance in lecture (30% total), report assignment given by each instructor (70% total)
Message from instructor(s)
We hope that this lecture will help you on your research in the future.
Course keywords
Carbohydrate acting enzymes, Anti-cancer drugs, Bioactive natural compounds, Glycoprotein
Office hours
Questions can be asked after class, or please request an appointment by email.
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
3/8/2019 10:44:42 AM