| Course title | |||||
| 生物生産科学フロンティア講義Ⅶ [Special Lectures on Frontier of Biological Production Ⅶ] | |||||
| Course category | Requirement | Credit | 0.5 | ||
| Department | Year | 1～ | Semester | 1st | |
| Course type | 1st | Course code | 05MP5108 | ||
| Instructor(s) | |||||
| 勝間 進, 天竺桂 弘子 [KATSUMA Susumu, TABUNOKI Hiroko] | |||||
| Facility affiliation | Faculty of Agriculture | Office | afjgxte/L1151 | Email address | |
| Course description |
|
In the silkworm, Lepidopteran insects, it has been known that a female sex determinant is present on the W chromosome over 80 years ago; however, its molecular mechanisms have been obscure. Our group discovered the female sex determinant factor in 2014. Surprisingly, this factor was piRNA which is a one of a small RNA molecule. Furthermore, piRNA was targeted to the male gene Masc transcribed from the Z chromosome. In this lecture, we will introduce recent findings on the sex determination mechanism of Lepidoptera insects revealed by Bombyx mori and the sexual manipulation mechanism related to it by Volvacia. |
| Expected Learning |
|
To obtain the knowledge of insect physiology and biochemistry, and how to apply this knowledge to industrial goods. Corresponding criteria in the Diploma Policy: See the Curriculum maps. (URL: https://www.tuat.ac.jp/campuslife_career/campuslife/policy/ ) |
| Course schedule |
|
1. Diversity and similarity in insect sex-determination system 2. History of sex determination research in silkworms 3. Finally found! piRNA determines sex of silkworm 4. Silkworm is a suitable model for piRNA research 5. Novel gene Masc play a changing to male and gene quantity compensation 6. Finding from the silkworm sex determination research - To elucidate the sexual control mechanism by Wolbachia |
| Prerequisites |
| Required Text(s) and Materials |
| The text will be introduced in lectures. |
| References |
| Some additional readings will be introduced in lectures. |
| Assessment/Grading |
| We evaluate by contribution in this class (30%), and assignment (70%). |
| Message from instructor(s) |
| We hope students improve their understanding of insect physiology and biochemistry. Also, we hope how student can use this knowledge. |
| Course keywords |
| insect sex determination; piRNA; Wolbachia; Masc |
| Office hours |
| Please get an appointment with your instructor by e-mail. |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 1/27/2020 4:55:54 PM |