| Course title | |||||
| 応用有機合成特論 [Advanced Organic Synthesis] | |||||
| Course category | courses for master's programs | Requirement | Credit | 2 | |
| Department | Year | ～ | Semester | 3rd | |
| Course type | 3rd | Course code | 1060203 | ||
| Instructor(s) | |||||
| 齊藤 亜紀夫, 山崎 孝 [SAITO Akio, YAMAZAKI Takashi] | |||||
| Facility affiliation | Faculty of Engineering | Office | afjgxte/L1151 | Email address | |
| Course description |
|
Heterocycles are important compounds widely found in the useful substances such as medicine drugs, agrochemicals and functional materials. Therefore, it is a clue leading to the development of novel useful materials to learn the chemical properties of the known heterocycles. In this course, the reactivities and synthetic methods of representative heterocycles were explained. In this course, lectures are given using Microsoft PowerPoint. In each lecture, handouts are distributed. |
| Expected Learning |
|
1. To understand concepts, systematic classifications, names and structures of various heterocycles. 2. To understand chemical functions, reactivities and synthetic methods of electron-rich and electron-poor heterocycles. 3. To understand latest synthetic methods of heterocycles and to explain them. Corresponding criteria in the Diploma Policy: See the Curriculum maps. |
| Course schedule |
|
1st lecture: The general remarks (functions, classifications, organized naming) of the heterocycle compounds 2nd lecture: Chemical functions, reactivities and synthetic methods of 5-membered heterocycles, Part 1 (pyrroles, furans, thiophenes) 3rd lecture: Chemical functions, reactivities and synthetic methods of 5-membered heterocycles, Part 2 (azoles) 4th lecture: Chemical functions, reactivities and synthetic methods of 6-membered heterocycles 5th lecture: Chemical functions, reactivities and synthetic methods of benzene-fused 5-membered heterocycles 6th lecture: Chemical functions, reactivities and synthetic methods of benzene-fused 6-membered heterocycles 7th lecture: Chemical functions, reactivities and synthetic methods of other ring-fused heterocycles 8th lecture: Chemical functions, reactivities and synthetic methods of nucleic acids 9th lecture: Heterocycles in Vitamines 10th lecture: Concepts and application of click chemistry 11-15th lectures: Investigation and presentation for latest synthetic methods of heterocycles. |
| Prerequisites |
|
It is desirable for students to have already studied about organic chemistry in the department of chemistry. Require preparation and review hours recommended by this university along with school hours (30 hours). Do preparation and review using textbooks and handouts. |
| Required Text(s) and Materials |
|
Handouts are distributed as textbooks. |
| References |
| ヘテロ環の化学：医薬品の基礎 國枝武久・永松朝文・日比野俐・前波勇・村上泰興 著（化学同人） |
| Assessment/Grading |
| Grades are given based 70% on the assignment and 30% on the presentation for latest synthetic methods of heterocycles. |
| Message from instructor(s) |
| Since this course supplies advanced contents of heterocycles, students should check the uncomprehended contents in basic organic chemistry. |
| Course keywords |
| Organic synthesis, heterocycle, drug development |
| Office hours |
| Whenever I am in my office, I take questions. |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/15/2019 2:49:06 PM |