Course title
生命分子反応特論   [Biomolecular Reaction]
Course category	courses for doctoral programs	Requirement		Credit	2
Department		Year	～	Semester	1st
Course type	1st	Course code	1080111
Instructor(s)
長澤 和夫, 櫻井 香里   [NAGASAWA Kazuo, SAKURAI Kaori]
Facility affiliation	Graduate School of Engineering	Office	afjgxte/L1151	Email address

Course description

In this course, synthesis of biologically active natural and unnatural compounds will be described. The topics are selected from the top journal in this field (JACS and Angewandte), and students will learn cutting edge science in this field. In the second half of this course, students will be required short presentation of natural product synthesis, which is given in the journal. Finally, elucidation of the mode of actions for the natural product will be discussed.

Expected Learning

Learn the basics of biomolecular reactions involving proteins, nucleic acids, and coenzymes. In addition, students will gain the ability to understand cutting-edge research on biomolecular reactions and communicate them easily to researchers in other specialized fields.

Course schedule

1. Guidance 2-7. Natural products synthesis (Taxol, Macrolides, Steroids, Alkaloids I, Alkaloids II, Guanidine alkaloids) 8-14. Students presentation 15. Summary pf the course (Chemical biology)

Prerequisites

Must have a course in organic chemistry in the master's course

Required Text(s) and Materials

Springer, by Hermann Dugas Bioorganic Chemistry

References

Tokyo Chemical Doujinshi, Yasuyuki Kita and Tetsuo Hiraoka Drug Discovery Chemistry-An Approach from Organic Synthesis

Assessment/Grading

presentation 80% quiz in evert term 20%

Message from instructor(s)

Find new chemistries in Bioorganic chemistry

Course keywords

nucleic acid, natural products, protein, sugar

Office hours

Monday, 12-14 pm

Remarks 1

Remarks 2

Related URL

Lecture Language

Japanese

Language Subject

Last update

2/22/2020 12:14:13 PM