| Course title | |||||
| 先端生命科学特論 [Advanced Life Science] | |||||
| Course category | Requirement | Credit | 0.5 | ||
| Department | Year | ～ | Semester | 1st | |
| Course type | 1st | Course code | 96212 | ||
| Instructor(s) | |||||
| 鈴木 智大（宇） [SUZUKI Tomohiro] | |||||
| Facility affiliation | United Graduate School Agricultural Science | Office | afjgxte/L1151 | Email address | |
| Course description |
|
" Chemical and bioinformatic analysis of naturally occuring biologically active substances from mushroom " Biologically active substances, even in trace amounts, show specific action on the physiology and behavior of living organisms by regulating their biological functions. In this lecture, the structure determination of small molecules/macromolecules (proteins) and elucidation of their biosynthesis through genome/RNA-seq analysis are introduced through the study of various biologically active substances from mushrooms. |
| Expected Learning |
|
1. Understanding of NMR and mass spectrometry methods for structure determination of small molecules/macromolecules (proteins). 2. Understanding of next generation sequencing for biosynthesis research. |
| Course schedule |
|
1. Studies on toxic substance(s) from the mushroom Pleurocybella porrigens. Pleurocybella porrigens is a poisonous mushroom that causes acute encephalopathy. In this lecture, the structure determination and biosynthesis research of toxic substances derived from this mushroom using NMR and mass spectrometer are reviewed in detail. 2. Studies on plant growth regulator(s) produced by the mushroom Lepista sordida. The structure determination of plant growth regulator(s) produced by Lepista sordida, which causes fairy ring disease and their biosynthetic pathway in plants are explained. |
| Prerequisites |
| Basic knowledge of subjects such as organic chemistry, biochemistry, and analytical chemistry is necessary. |
| Required Text(s) and Materials |
| N/A |
| References |
| N/A |
| Assessment/Grading |
| The grade will be determined by an examination during the lecture duration. |
| Message from instructor(s) |
| Please acquire basic knowledge on structure determination and biosynthesis research by attending classes and then consider applying it to your own research. |
| Course keywords |
| Office hours |
| Friday, 13: 00-16: 00 |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Language Subject |
| Last update |
| 2/25/2019 3:21:30 PM |