Course title
応用微生物学   [Applied Microbiology]
Course category   Requirement   Credit 2 
Department   Year 3  Semester 1st 
Course type 1st  Course code 01BN3129
Instructor(s)
蓮見 惠司, 鈴木 絵里子   [HASUMI Keiji, SUZUKI Eriko]
Facility affiliation Faculty of Agriculture Office afjgxte/L1151  Email address

Course description
Overview of applied microbiology and biotechnology focusing on the fundamental understanding of the molecular and evolutional bases.
The lecturer of this course has the firsthand experiences on research and development in a startup company as a side job for the development of his research results in the university. He will give a lecture based on his own experience.
Expected Learning
- Understanding the basis of applied microbiology
- Understanding examples of industrialized development
- Understanding the ability of microbes in relation to their evolutionary history

Corresponding criteria in the Diploma Policy: (B)
Please refer to the curriculum map at the following URL:
https://www.tuat.ac.jp/campuslife_career/campuslife/policy/.
Course schedule
1. Introduction
2. What is fermentation?
3. Microbial production of amino acids--(1) Glutamic acid
4. Microbial production of amino acids--(2) Lysine
5. Microbial production of nucleosides and nucleotides--(1) Inosine and guanosine
6. Microbial production of nucleosides and nucleotides--(2) Inosinic acid and guanylic acid
7. Antibiotics--(1) Overview and beta-lactams
8. Antibiotics--(2) Aminoglycosides, macrolides, and other antibiotics
9. Antifungal and antitumor microbial metabolites
10. Bioactive microbial metabolites--(1) Discovery and development of statins
11. Bioactive microbial metabolites--(2) Mechanism of the action of statins
12. Bioactive microbial metabolites--(3) Other compounds
13. Bioactive microbial metabolites--(4) Introduction to recent drug development
14. Microbial enzymes and their use as bioreactors and biosensors
15. Summary
Prerequisites
None
Required Text(s) and Materials
None, information to be provided if needed
References
Microbiology (free online textbook) at:
https://openstax.org/details/books/microbiology?Book%20details
Assessment/Grading
Short tests = 20%; term-end examination = 80%
Message from instructor(s)
It is interesting to understand unity and diversity of microbes
Course keywords
bacteria, fungi, metabolite, amino acid, alcohol, nucleotide, antibiotic, statin, bioactive natural product, drug discovery
Office hours
Please contact by email
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
2/28/2020 6:10:04 PM