Course title
病理学実習Ⅰ   [Practice in Veterinary Pathology Ⅰ]
Course category   Requirement   Credit 1 
Department   Year   Semester 3rd 
Course type 3rd  Course code 01VN3217
Instructor(s)
渋谷 淳, 吉田 敏則   [SHIBUTANI Makoto, YOSHIDA Toshinori]
Facility affiliation Faculty of Agriculture Office afjgxte/L1151  Email address

Course description
Based on the morphologic features of normal animals learned in the practice of animal anatomy, cultivate the ability to understand the tissue pathology on characteristic lesions that appear in organs and tissues in various diseases of companion animals and livestock, which are learned in Animal Special Pathology (A, B), as well as cultivating the observation ability to interpret the pathological condition at the individual level. In addition to gross observation of the lesions of organs and tissues of industrial animals detected at a meat inspection laboratory, learn practically how to conduct autopsy and observe pathological changes appeared in various organs throughout the body. By means of the practice in gross and histological pathology, cultivate comprehensive diagnostic ability of diseases. This subject is a course subject by a teacher with practical experience. In charge of toxicology, the instructor has experience in pathological diagnosis in toxicity tests, and gives lectures with examples of lesions in class.
Expected Learning
Corresponding criteria in the Diploma policy:
Please refer to the curriculum map of our university HP (3 policies).
https://www.tuat.ac.jp/campuslife_career/campuslife/policy/

1. Understand the procedure of necropsy of experimental animals, observation method of macroscopic lesions, and how to take findings.
2. Understand the techniques for autopsy of chickens, how to observe macroscopic lesions, and how to take findings. Depending on the situation, perform pathological dissection of dead animals and understand similar procedures.
3. Conduct a visual inspection of cattle and pig lesions detected at the meat inspection laboratory.
4. Understand the outline of tissue preparation for histopathology such as fixation and trimming of animal tissues, and sectioning and staining of embedded tissue specimens.
5. Understand how to observe the tissue slides for histopathological assessment using a microscopy.
6. Understand the morphological changes of the lesions in the circulatory system.
7. Understand the morphological changes of the lesions in the hematopoietic system.
8. Understand the morphological changes of the lesions in the respiratory system.
9. Understand the morphological changes of the lesions in the digestive system.
10. Understand the morphological changes of the lesions in the urinary system.
11. Understand the morphological changes of the lesions in the reproductive system.
12. Understand the morphological changes of the lesions in the nervous system.
13. Understand the morphological changes of the lesions in the musculoskeletal system.
14. Understand the morphological changes of the lesions in the skin and soft tissue.
Course schedule
Practice in Pathology is held during the 3rd semester of the 3rd grade and the 1st semester of the 4th grade, and carries out the following exercises.

3rd year, 3rd semester open
1. Description of how to prepare pathological specimens and how to use a microscope; Practice of observation of pathological tissue specimens of diseased animals: cardiovascular system lesions #1.
2. Observation practice of histopathological specimens of diseased animals: cardiovascular system lesions #2.
3. Observation practice of histopathological specimens of diseased animals: cardiovascular system lesions #3, hematopoietic system lesions #1.
4. Autopsy practice using normal rats.
5. Observation practice of histopathological specimens of diseased animals: hematopoietic system lesions #2.
6. Observation practice of histopathological specimens of diseased animals: hematopoietic system lesions #3.
7. Observation training of histopathological specimens of diseased animals: Experimentally induced toxic lesions in rodents.
8. Practice observation of pathological tissue specimens of diseased animals: hematopoietic system lesions #4, respiratory system lesions #1.
9. Histopathology sample preparation practice: Excision of tissue pieces, paraffin embedding, slicing of tissue sections, and HE staining preparation.
10. Observation practice of histopathological specimens of diseased animals: respiratory system lesions #2.
11. Observation practice of histopathological specimens of diseased animals: respiratory system lesions #3, digestive system lesions #1.
12. Observation practice of histopathological specimens of diseased animals: digestive system lesions #2.
13. Observation practice of histopathological specimens of diseased animals: digestive system lesions #3.
14. Practice of observing pathological tissue specimens of diseased animals: digestive system lesions #4.
15. Summary of the content of the 1st to 14th exercises, section diagnosis test.

4th year, 1st semester open
1. Observation practice of histopathological specimens of diseased animals: digestive system lesions #5.
2. Observation practice of histopathological specimen of diseased animal: Urinary system lesions #1.
3. Observation practice of histopathological specimen of diseased animal: Urinary system lesions #2.
4. Pathology of chickens (aged chickens).
5. Observation practice of histopathological specimens of diseased animals: genital system lesions #1.
6. Observation practice of histopathological specimens of diseased animals: genital system lesions #2.
7. Practice observation of pathological tissue specimens of diseased animals: nervous system lesions #1.
8. Practice observation of pathological tissue specimens of diseased animals: nervous system lesions #2.
9. Practice observation of pathological tissue samples of diseased animals: nervous system lesions #3.
10. Observation practice of histopathological specimens of diseased animals: musculoskeletal system lesions #1, integumentary system lesions #1.
11. Visual observation training of the affected organs (cow) of the meat inspection laboratory.
12. Visual observation and training of organs (pigs) detected by meat inspection laboratory.
13. Observation practice of histopathological specimens of diseased animals: integumentary system lesions #2.
14. Practice of observing pathological tissue specimens of diseased animals: integumentary system lesions #3.
15. Summary of the content of the 1st to 14th exercises, section diagnosis test.
Prerequisites
The students should have taken courses on veterinary anatomy, veterinary histology, veterinary physiology, veterinary biochemistry, veterinary microbiology, immunology, and general veterinary pathology. In addition to the practice time, refer to the training materials, textbooks, reference books, etc. that have been distributed, and do post-study to complete the sketch.
Required Text(s) and Materials
Use Animal Special Pathology (2nd Edition), Color Atlas of Animal Pathology (2nd Edition), both being edited by Japanese Society of Veterinary Pathology as textbooks. Powerpoint documents will also be handed out.
References
Veterinary Pathology Practice Manual, 2nd Edition. In addition, Pathologic Basis of Veterinary Disease (James F. Zachary ed., 6th edition, published by Elsevier), Pathology of Domestic Animals (Grant Maxie ed., 6th edition, published by Elsevier), Tumors in Domestic Animals (Donald J. Meuten ed., 6th edition, published by Wiley Blackwell) is a good reference for promoting professional understanding, as it has detailed commentary and abundant photographs and illustrations.
Assessment/Grading
More than 80% of the attendance to the practice of the 1st and 14th times in each semester is prerequisite for the assessment. Degree of activeness in the class, submission of reports (sketch), and tests for histopathological diagnosis using projected pathological images will constitute 20%, 40%, and 40% of your final grade, respectively.
Message from instructor(s)
Students should have studied well the contents in anatomy and histology classes at the 2nd grade, because knowledge of these courses is indispensable to them for conducting pathological diagnosis. They will use a textbook of Systemic Animal Pathology and also Color Atlas of Animal Pathology, both of which cover the contents in on-the-job pathological program.
Course keywords
Pathological anatomy, microscopical assessment, histopathological diagnosis
Office hours
13:00〜18:30. Your visits are always welcome.
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
2/21/2020 2:39:07 PM