| Course title | |||||
| 蛋白質・核酸科学 [Protein and Nucleotide Science] | |||||
| Course category | technology speciality courses | Requirement | Credit | 1 | |
| Department | Year | 2～4 | Semester | 3rd | |
| Course type | 3rd | Course code | 022169 | ||
| Instructor(s) | |||||
| 池袋 一典, 津川 若子, 黒田 裕 [IKEBUKURO Kazunori, TSUGAWA Wakako, KURODA Yutaka] | |||||
| Facility affiliation | Faculty of Engineering | Office | afjgxte/L1151 | Email address | |
| Course description |
|
Fundamental knowledge of relationship between the structure and function of protein will be explained. We also teache basic knowledge of the protein engineering especially, site directed mutagenesis . The application of the enzymes and proteins will be introduced. |
| Expected Learning |
| The students will know the relationship between the structure and funciton of proteins and how we can analysis and improve those fuctions with protein engineering. Commercialization is also very important process for the studetns in Dept. Engineering, so we will introduce those successful examples. |
| Course schedule |
|
The following issues will be lectured. 1. Fundamental understanding of the structure of ptoteins as polypeptides. 2. Fundamental methodologies for the analyses of protein structures. 3. The methodology for comparison of protein structures. 4. The methodology for structural prediction of proteins. 5. The methodology for prediction of interactions of proteins. 6. How to transform the E. coli with the target gene. 7. How to produce target proteins in E. coli. 8. How to change amino acid of the target protein (site directed mutagensis). 9. Nucleic acid engineering. 10. Aptamer 11. Commercially available enzymes. 12. The problems in commecialization of proteins. |
| Prerequisites |
| To better understanding, it is recommended to take the lecture of "Basic phycics", "Basic Chemistry" and "Basic biology". This is a part of learning the course of Biochemistry and Molecular biology. |
| Required Text(s) and Materials |
| Introduction of protein science, edited by Fumio Arisaka, Shokabo. |
| References |
| Assessment/Grading |
| This course is divided three parts, and in each of them, exam of report will be conducted and the grade is assessed considering the those three parts. |
| Message from instructor(s) |
| We will introduce the cutting edge reasearches and those are of course written in English. So the English reading is required for this lecture. |
| Course keywords |
| Office hours |
| Driday, 12-13 o'clock. |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 2/21/2020 2:16:53 PM |