| Course title | |||||
| 有機化学演習 [Exercises in Organic Chemistry] | |||||
| Course category | technology speciality courses | Requirement | Credit | 1 | |
| Department | Year | 2～4 | Semester | 3rd | |
| Course type | 3rd | Course code | 022381 | ||
| Instructor(s) | |||||
| 兼橋 真二 [KANEHASHI Shinji] | |||||
| Facility affiliation | Faculty of Engineering | Office | afjgxte/L1151 | Email address | |
| Course description |
|
"Exercises in Organic Chemistry" is a class of exercises to settle the contents of Organic Chemistry I, II and III as knowledge that can be used for understanding various phenomena in chemistry. Most of chemical and pharmaceutical industry and biotechnology is based on organic chemistry. You will not be able to master the fundamentals for organic chemistry by simply attending the lectures. It is essential to solve the problems by yourself for deep understanding of organic chemistry. In this course, therefore, you will be required to solve the problems from the textbooks (Paula Y. Bruice, Organic Chemistry) used in the Organic Chemistry I, II, and III. Exams will be given every week according to the course schedule announced in the course guidance. What each exam covers will also be given in the schedule. The problems in the exam will be assigned from the text for each chapter and/or will be similar to those found in the text. The course format consists of 1) reviewing the scheduled chapters, 2) exams for the corresponding chapters, and 3) explanation of how to solve the problems. |
| Expected Learning |
|
Objective of this course is to gain a solid understanding of basic organic chemistry by solving problems. The students will be able to explain various phenomena regarding organic chemistry or reactions based on your acquired knowledge. Corresponding criteria in the Diploma Policy: See the Curriculum maps. |
| Course schedule |
|
Week 1: Course Guidance Week 2: Electronic Structure and Bonding (Chapter 1): Chemical Bonding and Molecular Structure (Atomic Orbitals, Electron Configuration， Covalent Bonding and Its Presentation by Valence Bond and Molecular Orbital Methods, Hybridization and Molecular Structure), Polar Bonding (Dipole Moment and Formal Charge), etc. are involved. Week 3: Acids and Bases (Chapter 3): Definition of Acid and Base, Acid-Base Dissociation Equilibriums and Its pka vales, Structural Factors Determining Strength of Acids and Bases, etc. are involved. Week 4: Nomenclature and Stereoisomers (Chapters 3 and 4): Nomenclature of Basic Organic Compounds such as Alkanes and Cycloalkanes, Their Physical Properties, Representation of Structures, and Stereochemistry, etc. are involved. Week 5: Alkenes and Their Reactions (Chapters 5 and 6): Structures, Nomenclature, Basic Reactivities, Thermodynamics, and Kinetics, and Stereochemistry for Addition Reactions of Alkenes, etc. are involved. Week 6: Reactions of Alkynes (Chapter 7) and Delocalized Electrons and Their Effect on Stability, Reactivity, and pKa (Chapter 8) Week 7: Substitutions and Eliminations of Alkyl Halides (Chapters 9 and 10): Substitutions (SN1and SN2) and Eliminations (E1 and E2) of Alkyl Halides, etc. are involved. Week 8: Summary Mid-term Exam for week 1-7 Week 9: Reactions od Alcohols, Amines, Ethers, Epoxides, and Sulfur-containing Compounds (Chapter 11) and Chemistry of Benzene: Electrophilic Aromatic Substitution (Chapter 16): Nucleophilic Substitutions of Alcohols and Ethers, and Eliminations and Oxidations of Alcohols, and Reactions of Amines Thiols, Sulfides, and Sulfonium Salts are involved. Week 10: Organometallic Compounds (Chapter 12) and Radical Reactions (Chapter 13): Preparation of Organometallic Compounds, Cross-coupling Reactions, and Metathesis Reactions are involved. Stability of Radicals and Related Reactions, etc. are also included. Week 11: Carbonyl Compounds (Carboxylic Acid Derivatives, Aldehydes, and Ketones) (Chapters 16 and 17): Nomenclature of Aldehydes, Ketones, and Carboxylic Acid Derivatives such as Acid Chlorides, Anhydrides, Esters, and Amides, and Their Preparations and Reactions (Nucleophilic Acyl Substitutions, Nucleophilic Additions, and Wittig Reaction, etc.) are involved. Week 12: Carbonyl Alpha-Substitution Reactions (Chapter 18): Carbonyl Alpha-Substitution Reactions (Formation of Enolates, Their Alkylations and Halogenation etc.) and Condensation of Carbonyl Compounds (Aldol Reaction, Claisen Condensation, Michael Reaction, etc.) are involved. Week 13: Aromatic Compounds (Chapter 19): Chemistry of Benzene and Related Aromatic Compounds (Aromaticity, Huckel Rule, Electrophilic Aromatic Substitution Reactions, etc.) are involved. Week 14: Amines (Chapter 20): Reactions are Nomenclature, Preparation, Properties, and Reactions are involved. Week 15: Summary End-term Exam foe Week 9-14 |
| Prerequisites |
|
In the exercise, what each exam covers will be given in the schedule. For that reason, it is necessary to read the corresponding part of the text and to prepare such as solving the chapter problem (12 hours). After completion of the class, each person checks the answer, the wrong part is reconfirmed against the text, the corresponding answers, the commentary on the lesson etc. (3 hours). In addition to 30 hours that students spend in the class, students are recommended to perform the above task using the textbook and the references specified below. In completing this course, students will spend the standard amount of time as specified by the University. |
| Required Text(s) and Materials |
| Organic Chemistry (7th edition), Paula Y. Bruice, Pearson (2013) |
| References |
|
Organic Chemistry, John E. McMurry, Brooks/Cole Pub Co Yuki Kagaku Enshu, G.Yamamoto, M. Iyoda, S. Toyota, Tokyo Kagaku Dojin |
| Assessment/Grading |
| Your grade will be determined largely by a total score of exam points in principle （weekly exams (50%), and mid and end-term exams (50%)）. A degree of participation in class may be considered. You are expected to attend the course guidance and all exam sessions to pass the course. |
| Message from instructor(s) |
| The scope of each exam will be announced in the course guidance. The students should prepare for the exams. It is essential for understanding organic chemistry to think for yourself. |
| Course keywords |
| Organic Reactions, Theoretical Organic Chemistry, Synthetic Organic Chemistry, Structural Organic Chemistry |
| Office hours |
| Dr. Shinji Kanehashi: Mon, 10:30-12:00 (Room:BASE-324) |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/3/2020 10:19:36 PM |