Course title
生命科学特別講義(ゲノム工学)   [Special Lecture on Life Science(Genome Engineering)]
Course category technology speciality courses,ets.  Requirement   Credit 1 
Department   Year 34  Semester 1st 
Course type 1st  Course code 025102
Instructor(s)
中村 史, 金 賢徹, 中村 徳幸   [NAKAMURA Chikashi, KIM Hyonchol, NAKAMURA Noriyuki]
Facility affiliation Graduate School of Engineering Office afjgxte/L1151  Email address

Course description
The lecture introduces state of art in biotechnology to develop an understanding about the related field.
This special lecture is presented by AIST and RIKEN researches involved in partner graduate school.
About a biotechnology research developed in the field of life science of AIST, explain about necessary basic knowledge to accomplish study, comment on technique used in leading-edge of study, and lecture with the future perspective from its background.
Expected Learning
Be able to prepare agenda as a student who will be involved with life science, biotechnology research in future.
Course schedule
Week1(4/ 9):Introduction Chikashi Nakamura
Week2(4/16):Measurement Techniques 1 Hyonchol Kim
Week3(4/23):Measurement Techniques 2 Hyonchol Kim
Week4(4/30):Genome Editing 1 Yoshio Kato
Week5(5/ 7):Genome Editing 2 Yoshio Kato
Week6(5/14):Cell Engineering 1 Noriyuki Nakamura
Week7(5/21):Cell Engineering 2 Noriyuki Nakamura
Week8(5/28):Motor Protein 1 Nobuhisa Umeki
Week9(6/ 4):Motor Protein 2 Nobuhisa Umeki
Week10(6/11):Biosensing Technology 1 Hyonchol Kim
Week11(6/18):Biosensing Technology 2 Hyonchol Kim
Week12(6/25):Introduction to Bioengineering Chikashi Nakamura
Week13(7/ 2):Gene Transfer Technology Chikashi Nakamura
Week14(7/ 9):Endocrine Disrupter and Immunity Chikashi Nakamura
Week15(7/16):Artificial Antibody Chikashi Nakamura


Week2-3:Measurement Techniques 1-2, these lectures are focusd on prnciples and applications of various microscopies to measure functions of single molecules and single cells.
Week4-5:Genome Editing 1-2, we introduce Zinc-Finger Nuclease (ZFN), which is an advanced technology for targeted manipulation of the cellular genome.
Week6-7:Cell Engineering 1-2, lectures about research and development of the basic materials related to tissue engineering (or regenerative medicine),the measuring method of cell proliferation and activity are given. Description of the fundamental knowledge and the ethical viewpoint related to an embryonic stem cell and the cloned animals is also given.
Week8-9:Motor Protein 1-2, this section will introduce the function of motor proteins and its application, especially focusing on myosin-actin system.
Week10-11:Biosensing Technology 1-2, these lectures are focused on applications of nanomaterials and nanofabrications for target detections in single cell level.
Week12-15:The lectures will be focused on nanobiotechnology. Development of biosensor or regearative medicine using nanoneedle will be introduced, aiming to make deep undestandings of the trends in biotechnology. The subject of report will be presented in the lecture week12.
Prerequisites
None
Required Text(s) and Materials
None
References
Molecular Biology of the Cell
Watson Molecular Biology of the Gene, James D. Watson
Immunology, Ivan Roitt
Assessment/Grading
Contribution to the lectures:50%(Mini-exam, Practice), Report:50% (Theme of report will be informed in the 12th Lecture and dead line of report submission is the 15th lecture.)
Message from instructor(s)
・No conditions for this course. Students who are interested in advanced research will be welcomed.
・Attendance will be counted by mini-exam or call over at each lecuture.
・Any questions will be welcomed during or after the lecutre, or you can come to office during the following office hour, or by e-mail.
Course keywords
Tissue Engineering,Cell Engineering,Genome Editing,Biosensor,Peptide Engineering,Genomic Engineering,Nanobiotechnology
Office hours
Every Thursday, Friday, 10:00〜18:00 Office:Room404, Bldg11
Remarks 1
Remarks 2
Related URL
https://unit.aist.go.jp/bmd/biomed-cme/index_en.html
Lecture Language
Japanese
Language Subject
Last update
3/16/2020 12:27:00 PM