Course title
国際応用生命化学Ⅱ   [International Life and Biological ChemistryⅡ]
Course category   Requirement   Credit 2 
Department   Year 1  Semester 3rd 
Course type 3rd  Course code 05ic0006
Instructor(s)
山形 洋平, 矢部 富雄, 松村 清隆, 西宗 裕史, 西河 淳   [YAMAGATA Yohei, YABE Tomio, MATSUMURA Kiyotaka, NISHIMUNE Hiroshi, NISHIKAWA Atsushi]
Facility affiliation Faculty of Agriculture Office afjgxte/L1151  Email address

Course description
This lecture will provide international trends in gene analysis, biological new function development, medical field development, etc. in fields of applied life chemistry, biomolecular chemistry and physiological biochemistry.
Expected Learning
To understand the international trends in gene analsys ,new biological function devlopmetn, medical science in the fileds of applied life chemistry, biomolecular chemistry and physiological biochemistry.
Course schedule
Prof. Yabe
1:Regulation of cell function via heparan sulfate
2:Small intestinal villus elongation by dietary fiber pectin
3:Characterization of specific sugar chains of human milk-derived glycoproteins
4:Cell protection from antioxidative stress by royal jelly-derived peptide
5:Promotion effect of collagen production by food ingredients

Pro.Matsumura
1:Biomolecules and bioactive molecules
2:Chemical communication in marine organisms
3:Larval settlement and biofouling
4:Settlement cues and bio-signals
5:Omics approach for bio-signal study

Prof. Nishimune
1.Lecture 1
 a.Cell-Cell junctions
 b.The extracellular matrix of animals
2.Lecture 2 and active learning discussion
 a.The extracellular matrix of animals 2
 b.Active learning (1), the role of cell adhesion molecule
   *Peixoto, R.T., et al. Neuron 76, 396 (2012).
3.Lecture 3
 a.Cell-matrix junctions
4.Lecture 4 and active learning discussion
 a.Cell-matrix junctions2
 b.Active learning (2), the role of extracellular matrix
   **Fung, C., et al. Molecular biology of the cell 19, 797 (2008).
5.Lecture 5
 Super resolution microscopy
Prerequisites
Prof. Nishimura: Students are required to attend lecture 2 and 4 to participate in the discussion.
Students are recommended to prepare for and revise the lectures, spending the standard amount of time as specified by the university in addition to the attendance of lecture.
Required Text(s) and Materials
Prof. Yabe:Prepare based on the necessity
Prof. Matsumura:Prepare based on the necessity
Prof. Nishumune:Following research papers will be used in the active learning discussion session. Follow the link provided below to download the PDF file of the papers.
   *Peixoto, R.T., et al. Neuron 76, 396 (2012).
   https://www.ncbi.nlm.nih.gov/pubmed/?term=Peixoto%2C+R.T.%2C++Neuron+76%2C+396+(2012

   **Fung, C., et al. Molecular biology of the cell 19, 797 (2008).
   https://www.ncbi.nlm.nih.gov/pubmed/?term=Fung%2C+C.%2C+Molecular+biology+of+the+cell+19%2C+797+(2008
References
Prof. Yabe:Essentials of Glycobiology 3rd Ed., Varki et al., Cold Spring Harbor Laboratory Press, 2017.
Prof. Nishumune:Molecular Biology of the Cell, Sixth edition from Garland Science, Chapter 19
Assessment/Grading
Prof. Yabe:A report
Prof. Matsumura:A report
Prof. Nishumune:According to a report described below.
Report
Select one research paper reporting cell adhesion mechanisms in plants. Write a report describing the followings: (1) full reference information of the selected paper, (2) summary of the results, (3) innovative aspect of the study, and (4) significance of the new findings. The report should be a one-page document using 11-point Arial font and single-spaced lines. It is recommended to use paragraphs and section headers for formatting the report. Submit electronically by email the one-page report and a PDF file of the selected research publication.
Message from instructor(s)
Prof. Yabe:In this lecture, I will outline our recent researches, focusing on research background and methods.
Prof.Matsumura:I hope you are interested in the wonders of marine life and the clever strategy using bio-signals.
Prof. Nishimune:The course will be taught in English by combining lecture and journal club style discussion (active learning). Students are required to attend lecture 2 and 4 to participate in the discussion.
Course keywords
Prof. Yabe; proteoglycans, dietary fibers, glycans, royal jelly, collagen. Prof.Matsumura; bio-active molecules, chemical communication, marine organisms, barnacle, larval settlement, bio-signals, omics. Prof. Nishimune; Cell junction, Cell adhesion, Extracellular Matrix.
Office hours
Please contact by email.
Remarks 1
Please check for the syllabus changes due to the spread of COVID-19 infection in Google Classroom.
Remarks 2
Related URL
Lecture Language
English
Language Subject
Last update
8/31/2020 6:42:50 PM