Course title
応用生命化学特論Ⅵ   [Special Lecture on Applied Biological Chemistry Ⅵ]
Course category   Requirement   Credit 1 
Department   Year 1  Semester 2nd 
Course type 2nd  Course code 05lc0112
Instructor(s)
北野 克和, 舘川 宏之, 矢追 克郎, 殿塚 隆史   [KITANO Yoshikazu, TACHIKAWA Hiroyuki, YAOI Katsurou, TONOZUKA Takashi]
Facility affiliation Faculty of Agriculture Office afjgxte/L1151  Email address

Course description
[Objective] This course provides special topics in the field of applied biological chemistry.

[Synopsis]
Dr. Tachikawa and Dr. Yaoi, who are part-time lecturers, take charge of this course.

TACHIKAWA, Hiroyuki (The University of Tokyo)
Organisms use membranes to maintain their lives. Cells are separated from the outside by the cell membrane, and organelles are surrounded by the organelle membrane. Each of these biological membranes is formed to have a characteristic shape and an appropriate size, and abnormal morphogenesis of the membrane can cause diseases in human. In this lecture, you will learn about the molecular mechanism of morphogenesis of biological membranes. In addition, we will learn about yeast genetics research, which has been useful in elucidating various biological phenomena including biological membrane formation.

YAOI, Katsuro (AIST, National Institute of Advanced Industrial Science and Technology)
The “enzyme” is industrially used in various fields as a “biocatalyst having a low environmental load”, and enzymatic reactions are performed at normal temperature and pressure. Industrial enzymes are mainly produced by microorganisms, and to study the enzymes, obtaining of novel useful microorganisms, analysis of biochemical properties and three-dimensional structure determination, modification of enzymatic functions such as enzyme activity, substrate specificity, and stability. Various technologies such as the mass production technology of enzymes by microorganisms are necessary to
study industrial enzymes. In this lecture, an overview of technologies will be provided, and some examples of the studies will be shown.

Expected Learning
[TACHIKAWA Hiroyuki]
- Understanding how organisms form and use membrane structures.
- Understanding the importance of research using yeast in this field.

[YAOI Katsuro]
- Understanding the obtaining and analyzing methods of enzymes used in industry
- Understanding some studies for obtaining and analyzing novel useful microorganisms

Corresponding criteria in the Diploma Policy: (A) and (D)
Please refer to the curriculum map at the following URL:
https://www.tuat.ac.jp/campuslife_career/campuslife/policy/
Course schedule
[TACHIKAWA Hiroyuki] (Date: September 28, 2020)
1. Importance of research on eukaryotic cells using yeast as a model system
2. Organelle morphogenesis and membrane contact sites
3. Membrane traffic in the cell
4. Research on developmental process of yeast

[YAOI Katsuro] (Date: September 17, 2020)
1. Overview of industrial enzymes
2. Analytical technologies of enzymes
3. Obtaining of novel useful microorganisms
4. Examples of the studies of industrial enzymes
Prerequisites
Students need to preview and review for an amount of time as indicated in the student guidelines of TUAT, in addition to the attendance of lecture.
Required Text(s) and Materials
Handouts will be provided if needed.
References
References will be shown if needed.
Assessment/Grading
performance in lecture (30%), report assignment (70%)
Message from instructor(s)
Questions can be asked after class.
Course keywords
enzyme, micro-organism, membrane
Office hours
Questions can be asked after class.
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
4/20/2020 1:23:16 PM