Course title
分子生物工学特論   [Molecular Bioengineering]
Course category	courses for doctoral programs	Requirement		Credit	2
Department		Year	～	Semester	3rd
Course type	3rd	Course code	1080109
Instructor(s)
新垣 篤史   [ARAKAKI Atsushi]
Facility affiliation	Faculty of Engineering	Office	afjgxte/L1151	Email address

Course description

Students will learn about research trends and analytical techniques used in genomics, transcriptomics, proteomics, metabolomics and bioinformatics, which brought about technological innovations in the field bioscience, in two aspects including biochemistry-based commentaries and circumstances of development. After listening to these lectures, each student will read papers and other materials in English in the pertinent fields, put what they have learned into a presentation, and deliver it. Proposing and debating problems during the lessons, students will be given an opportunity to participate in active discussion among themselves.

Expected Learning

(1) You understand and can explain principles of omics analyses. (2) You can select method and analytical equipment which are appropriate for your research tasks. (3) You can propose solutions for tasks and/or problems of your research.

Course schedule

Technological innovation has rapidly progressed in biotechnology-related fields through research in biochemistry, genetic engineering, molecular biology (engineering) and genome engineering. In this advanced course of biochemistry, focusing on research trends and analytical techniques used in genomics, transcriptomics, proteomics, metabolomics and bioinformatics, scholastic findings and circumstances of development will be integrally explained. The lectures will introduce latest research reports together with general approaches in genomics and other areas and, after these lectures, students will give their own presentations. Each student will be required to choose one or another of scholastic papers concerning elemental technologies currently in the research stage to development or practical application stages in the related fields, and read it in preparation for the presentation he or she will make in the latter half of the course. A summary of the contents of such a paper will be presented, followed by a Q&A session and discussion, which will reveal his or her level of understanding. 1. Introduction 2. Genome analysis 3. Transcriptome analysis 4. Presentation 1 5. Proteome analysis 6. Presentation 2 7. Metabolome analysis 8. Presentation 3 9. Point of care technologies 10. Presentation 5 11. Chip I 12. Presentation 6 13. Chip II 14. Presentation 6 15. Conclusion

Prerequisites

Students should have basic knowledge in biochemistry, genetic engineering, molecular biology, biotechnology, and genome engineering. Desirably, they should have acquired credits in biochemistry and molecular biology.

Required Text(s) and Materials

Printed materials will be distributed as appropriate.

References

MURAMATSU Tadashi, translation supervisor, Genome 2 (2003), Medical Science International; Bunshi Saibo Seibutsu-gaku (Molecular cell biology) (in two volumes), translated by NODA Haruhiko et al., Tokyo Kagaku Dojin; MATSUNAGA Tadashi, ed. and author, Seimei Kagaku eno Shotai (2002) (Invitation to life engineering, Asakura Shobo

Assessment/Grading

Your final grade will be evaluated by response to questions and participation to discussion (30%), and presentation (70%). The evaluation of the presentation will take into account the presented contents of the paper in English translated by the student, the Q&A session and his or her participating attitude in the discussion based on the Q&A.

Message from instructor(s)

This class includes a broad range of technical discussions taking up topics which would prove useful in the students’ workplaces for research.

Course keywords

Genomics, proteomics, transcriptomics, metabolomics, bioinformatics, biochip

Office hours

3 to 5 p.m. every Monday

Remarks 1

Remarks 2

Related URL

Lecture Language

Japanese

Language Subject

Last update

3/16/2020 1:56:29 PM