Course title
動物病理学各論Ｂ（他臓器・組織）   [Systemic Veterinary Pathology B]
Course category		Requirement		Credit	2
Department		Year	4～	Semester	1st
Course type	1st	Course code	01VN4213
Instructor(s)
渋谷 淳, 吉田 敏則   [SHIBUTANI Makoto, YOSHIDA Toshinori]
Facility affiliation	Faculty of Agriculture	Office		Email address

Course description

Based on the understanding of Animal General Pathology, this learning course provides knowledge on morphological changes and pathological condition of lesions that appear in each organ or each organ system of animals as a course of Animal Special Pathology A at the 2nd semester of the 3rd grade and as a course of Animal Special Pathology B at the 1st semester of the 4th grade. Knowledge on this organ pathology plays an introductory role for clinical veterinary medicine. This knowledge also provides basics for toxicopatholological analysis of chemicals using experimental animals. This subject is a course subject by a teacher with practical experience. In charge of toxicology, the instructor has experience in pathological diagnosis in toxicity tests, and gives lectures with examples of lesions in class.

Expected Learning

Corresponding criteria in the Diploma policy: Please refer to the curriculum map of our university HP (3 policies). https://www.tuat.ac.jp/campuslife_career/campuslife/policy/ There are a variety of diseases including neoplasms that can be observed in farm animals, companion animals and experimental animals. Animal General Pathology is a discipline that deals with the study of responses and rules to all diseases, taking into account all the pathogenic factors and morbid circumstances, which can be found in different animals, but always from a general point of view. The Animal General Pathology includes understanding of basic knowledge necessary for morphological analysis of lesions developed in each disease of animals, as well as acquisition of pathological terms necessary for conduct of diagnosis in practice. In the course of Animal Special Pathology B, pathological lesions that appear in following organs in animals are dealt in terms of the understanding of pathogenesis as well as the comparative pathological viewpoint. 1. Urinary system (kidney, ureter, bladder, urethra): For example, (1) can explain the cause, pathogenesis and classification of glomerulonephritis, (2) can explain the pathological features of renal tubular lesions, (3) can explain the pathological features of acute and chronic nephritis, and (4) can explain the pathological features of papillary necrosis and other urinary tract lesions. 2. Reproductive organs (testis, epididymis, vas deferens, scrotum, male accessory gonads [seminal vesicle, prostate, urethral bulb], penis, foreskin, ovary, fallopian tube, uterus, placenta, cervix, vagina, vulva, mammary gland): For example, 1) explain the cause and pathological features of orchitis, (2) can explain the classification of testicular tumors and ovarian tumors, (3) can explain ovarian and uterine diseases, and (4) can explain the pathological features of infections that cause abnormal birth [abortion, stillbirth]. 3. Endocrine system (pituitary gland, thyroid gland, parathyroid gland, adrenal gland, other endocrine organs): For example, (1) can explain pathologically the cause, classification of goiter, (2) can explain pathological features of thyroiditis, (3) can explain the cause, pathophysiology and pathological features of hyperthyroidism and hypothyroidism of parathyroid gland, and (4) can explain the pathophysiological features of Cushing's syndrome. 4. Nervous system (brain, spinal cord, peripheral nerve): For example, (1) can explain fundamental pathological changes of nervous system, (2) can explain classification of encephalitis and meningitis, pathological features, (3) can explain the pathological features of nutritional diseases and toxic diseases in the nervous system, (4) can explain congenital and perinatal encephalopathy, hydrocephalus, and (5) can explain the pathological features of spinal cord degenerative diseases and peripheral nerve diseases. 5. Sensory organs (eye, ear): For example, (1) can explain the pathogenesis and pathological features of cataract and glaucoma, (2) can explain the pathological features of keratoconjunctivitis, uveitis, and (3) can explain the pathological features of ear diseases. 6. Musculoskeletal system (bone, joints, tendons, skeletal muscles): For example, (1) can explain the pathological features of metabolic bone disease and toxic bone disease, (2) can explain the pathological features of bone diseases caused by circulatory disorders, (3) can explain the causes and pathological features of joint disease, (4) can explain the basic lesion of skeletal muscle, (5) can explain the pathological features of inflammatory myopathy, (6) can explain the classification and pathological features of neurogenic myopathy, and (7) can explain the classification and pathological features of myogenic myopathy. 7. Integumentary system (skin): For example, (1) can explain basic skin lesions, (2) can explain the histologic features of dermatitis and representative diseases, (3) can explain the sub-allergic dermatitis, (4) can explain the classification and pathological features of autoimmune skin diseases, and (5) can explain the pathological features of representative skin tumors.

Course schedule

In the class of Veterinary Special Pathology B (Other organs and tissues), lecture is conducted on pathological features and pathogenesis of representative lesions that appear in following organs, following the class of Veterinary Special Pathology A at the 3rd semester of the 3rd grade. The mid-term exam (1st to 6th session) and the final exam (7th to 15th session) will be conducted during the class period. Special Animal Pathology B (Other Organs / Tissues) (4th grade, 1st semester): 1. Urinary tract #1 (Textbook, Chapter 6, 259-279): Anatomy and physiology of the kidney, congenital anomalies, glomerular diseases, and tubule and interstitial diseases. 2. Urinary tract #2 (Textbook, Chapter 6, 280-294): Renal circulatory disturbance, parasite infections, tumors; Anatomy and physiology of ureter, bladder and urethra, congenital anomaly, ureteral calculus, inflammation, and tumors. 3. Genital tract #1 (Textbook, Chapter 7, 295-303) : Anatomy and physiology of the testis, epididymis, vas deferens, and scrotum, congenital anomalies, degeneration, orchitis, epididymitis, scrotitis, tumors; Anatomy and physiology of gonads (seminal vesicle, prostate, urethral bulb), congenital anomalies, hypertrophy, inflammation, and tumors; Anatomy and physiology of penis and foreskin, scrotal and preputial inflammation, and tumors. 4. Genital tract #2 (Textbook, Chapter 7, 303-328): Anatomy and physiology, development and congenital anomalies, metabolic disorders (degeneration, degenerative changes), cystic diseases, tumors; hydrosalpinx, salpingitis, pylosalpinx, oviductal tumor of chicken; uterine anatomy / physiology, congenital anomalies, displacement, endometrial hyperplasia-related abnormalities, inflammation, and tumors; placenta: anatomy and physiology, polyhydramnios, excessive allantoic fluid, amniotic plaque, calcification, abortion, and stillbirth; uterine cervix, vagina, vulva: anatomy and physiology, cyst, inflammation, and tumors; mammary gland: anatomy and physiology, mastitis, tumors. 5. Endocrine organ (Textbook, Chapter 10, 385-406): Overview; anatomy and physiology of the pituitary, cyst, hypopituitarism, tumors; anatomy and physiology of the thyroid, congenital anomalies, goiter, toxic goiter (hyperthyroidism), causes and systemic effects of hypothyroidism, and tumors; anatomy and physiology of the parathyroid glands, parathyroid cyst, hyperthyroidism, and tumors; anatomy and physiology of the adrenal glands, congenital anomalies, atrophy of the adrenal cortex, degeneration, necrosis, chronic adrenocortical insufficiency, hyperadrenocorticism, tumors and tumor-like lesions; other endocrine organs: pineal body, chemoreceptor. 6. Summary of the lecture contents from the 1st to the 5th, and mid-term examination. 7. Nervous system #1 (Textbook, Chapter 8, 329-372): Brain anatomy and physiology, postmortem changes, and congenital abnormalities. 8. Nervous system #2 (Textbook Chapter 8, 329-345): cerebral circulatory disturbance, trauma, nutritional disorders, poisoning, age-related changes, and transmissible spongiform encephalopathy. 9. Nervous system #3 (Textbook, Chapter 8, 346-365): Encephalitis, and brain tumors. 10. Nervous system #4 (textbook, Chapter 8, 365-372): Anatomy and physiology of the spinal cord, congenital anomalies, degenerative diseases; peripheral nerve injury, mechanical injury, nutritional diseases, poisoning, inflammation, and tumors. 11. Sensory organs (Textbook, Chapter 9, 373-384): Anatomy and physiology of eyes, postmortem change, congenital anomalies, retinal detachment, retinal degeneration, cataract, glaucoma, inflammation, tumors; ear anatomy and physiology, external ear diseases, middle ear diseases, inner ear diseases, and tumors and tumor-like diseases. 12. Musculoskeletal system (Textbook, Chapter 11, 407-431): Anatomy and physiology of the bone, physical damage and reaction of bone, congenital abnormalities, metabolic diseases, circulatory disturbance, osteoarthritis, bone hyperplastic diseases and bone cysts, and tumors; joints and tendons: anatomy and physiology, congenital abnormalities, degenerative joint disease, arthritis, tendonitis, and tumors; skeletal muscle: autopsy and physiology, general lesions, circulatory disturbance, and muscle diseases of animals. 13. Integumentary system #1 (Textbook, Chapter 12, 433-453): Anatomy and physiology of the skin, basic lesions, congenital diseases, differentiation abnormality of the epidermis, pigmentation, lesion by physicochemical stimulation and light stimulation, nutrition-related lesions, endocrine-related lesion, allergic dermatitis, and immune-mediated skin diseases. 14. Integumentary system #2 (Textbook, Chapter 12, 453-478): infectious diseases of the skin, other skin diseases, skin tumors. 15. Summary of the 7th to 14th lecture contents, and final exam.

Prerequisites

It is necessary to take course of cell biology, genetics, veterinary anatomy, veterinary histology, veterinary physiology, veterinary biochemistry, veterinary microbiology, immunology, and animal general pathology before taking this class. In addition to the 15 times of class time, refer to the distributed lecture materials, textbooks, reference books, etc. and perform pre / post learning.

Required Text(s) and Materials

Use Animal Special Pathology (3rd Edition), Color Atlas of Animal Pathology (2nd Edition), both being edited by Japanese Society of Veterinary Pathology as textbooks. Powerpoint documents will also be handed out.

References

Veterinary Pathology Practice Manual, 2nd Edition. In addition, Pathologic Basis of Veterinary Disease (James F. Zachary ed., 6th edition, published by Elsevier), Pathology of Domestic Animals (Grant Maxie ed., 6th edition, published by Elsevier), Tumors in Domestic Animals (Donald J. Meuten ed., 6th edition, published by Wiley Blackwell) is a good reference for promoting professional understanding, as it has detailed commentary and abundant photographs and illustrations.

Assessment/Grading

We will evaluate the grades based on the mid-term and final regular exam scores. Attendance points are not included in the grades, but if students are absent three or more times in classes up to the mid-term exam and in classes after mid-term exam, students will not qualify for the exam. If the score does not reach 60 in each test, perform one additional test. The percentage of points, points of evaluation, and timing of the examination are as follows: Mid-term exam 50%: In the 6th lecture, students will be tested on their knowledge and understanding of the lecture content from the 1st to the 5th lectures, and evaluated comprehensively. Final exam 50%: In the 15th session, students will be tested on their knowledge and understanding of the contents of the lectures from the 7th to 14th sessions, and evaluated comprehensively.

Message from instructor(s)

Pathology is one of the academic disciplines required for the National Veterinary Medical Practitioners Qualifying Examination. Animal Pathology is positioned between basic veterinary classes and clinical classes, and thus, it is necessary to have knowledge on anatomy, histology, immunology, and microbiology to have appropriate understanding of lesions. It will be difficult to have appropriate understandings on clinical classes, such as veterinary surgery and veterinary internal medicine.

Course keywords

Pathological lesions in major organs, Degenerative changes, Adaptive cellular changes and abnormalities in cellular differentiation, Circulatory disturbances, Inflammation, Immunopathology, Oncology, Malformation.

Office hours

13:00〜18:30. Your visits are always welcome.

Remarks 1

E-mail address where you can be reached mshibuta@cc.tuat.ac.jp

Remarks 2

Related URL

https://tat-lvp.amebaownd.com

Lecture Language

Japanese

Language Subject

Last update

2/22/2021 5:41:31 PM