Course title
有機化学Ⅳ   [Organic ChemistryⅣ]
Course category technology speciality courses  Requirement   Credit 2 
Department   Year 24  Semester 3rd 
Course type 3rd  Course code 022385
Instructor(s)
齊藤 亜紀夫   [SAITO Akio]
Facility affiliation Faculty of Engineering Office afjgxte/L1151  Email address

Course description
This course can be recognized as the application after finishing studies of organic chemistry I to III. Students study proteins, nucleotides, sugars and vitamin during this lecture, and for understanding these subjects especially on metabolic pathways, combination of knowledge about such carbonyl compounds as amides, esters, aldehydes and amines and phosphonic acids are highly required. Thus, it is desirable for students to confirm issues already studied in previous lectures after having explanations at the class.
In this course, lectures are given using Microsoft PowerPoint. In each lecture, handouts are distributed.
Google Classroom Code: spo6h2m
Expected Learning
1. To understand properties, reactions and synthetic methods of amines.
2. To understand properties, reactions and synthetic methods of bio-related substances (sugars, peptides, nucleic acids, vitamins).
3. To understand metabolic pathways from the viewpoint of the organic chemistry.

Corresponding criteria in the Diploma Policy: See the Curriculum maps.
Course schedule
1st lecture: Properties,reactions and synthetic methods of amines. (Chapter 20: 20.1-20.4)
2nd lecture: Properties,reactions and synthetic methods of heterocyclic amines. (Chapter 20: 20.5-20.8)
3rd lecture: Classifications and stereochemistries of sugars. (Chapter 21: 21.1-21.4, 21.15-21.19)
4th lecture: Properties, reactions and synthetic methods of sugars.(Chapter 21: 21.5-21.14)
5th lecture: Properties, separation and synthetic methods of amino acids.(Chapter 22: 22.1-22.7)
6th lecture: Properties, structures and synthetic methods of peptides and proteins. (Chapter 22: 22.8-22.17)
7th lecture: Summary of 1st-6th lectures, midterm examination
8th lecture: Catalysis in organic reactions. (Chapter 23: 23.1-23.7)
9th lecture: Catalysis in biological reactions. (Chapter 23: 23.8-23.12)
10th lecture: Coenzyme I: Niacin, riboflavin, thiamine, biotin. (Chapter 24: 24.1-24.4)
11th lecture: Coenzyme II: Vitamin B6, B12, Niacin, vitamin K. (Chapter 24: 24.5-24.8)
12th lecture: Metabolic pathway: Catabolism of lipids, sugars and proteins. (Chapter 25: 25.1〜25.9)
13th lecture: Metabolic pathway: Citric acid cycle. Anabolism of sugars, terpenes and amino acids. (Chapter 25: 25.10〜25.18)
14th lecture: Properties,structures and roles of nucleic acid. (Chapter 26)
15th lecture: Summary of 1st-14th lectures, term examination
Prerequisites
This course is classified in technology speciality courses and provides one of the department-recommended organic chemistry subjects.
Require preparation and review hours recommended by this university along with school hours (30 hours). Do preparation and review using textbooks and handouts.
It is desirable for students to have already studied about organic chemistry I to III.
Required Text(s) and Materials
Paula Y. Bruce, “Organic Chemistry 7th Edition”ISBN978-4-7598-1585-6
References
General biochemical textbooks: e.g., Voet’s basic biochemistry
Assessment/Grading
Grades are given based 50 % on the score of midterm examination and 50% on the score of midterm examination.
Message from instructor(s)
Since this course supplies advanced contents of organic chemistry I to III, students should check the uncomprehended contents in organic chemistry I to III. As preparation, it is recommended that you read the text book and solve the exercises.
Course keywords
amines, heterocycles, sugars, peptides, nucleic acids, vitamins, metabolism
Office hours
Whenever I am in my office, I take questions.
Remarks 1
Grade points distribution in 2020: S X%, A X%, B X%, C X%, D X%.
Remarks 2
Related URL
http://www.tuat.ac.jp/~akio-sai/index.html
Lecture Language
Japanese
Language Subject
Last update
9/8/2021 4:39:04 PM