Course title
ナノバイオエンジニアリング   [Nanobioengineering]
Course category technology speciality courses  Requirement   Credit 1 
Department   Year 34  Semester 1st 
Course type 1st  Course code 023158
Instructor(s)
中村 史, 加藤 義雄, 山岸 彩奈, 金 賢徹   [NAKAMURA Chikashi, KATO Yoshio, KIM Hyonchol]
Facility affiliation Graduate School of Engineering Office afjgxte/L1151  Email address

Course description
In this lecture, you will study the most advanced research related to bioengineering that is actually being conducted in the department of lifescience and Biotechnology (https://www.aist.go.jp/aist_e/dept/en_dlsbt.html) of the National Institute of Advanced Industrial Science and Technology (AIST), especially research related to nano-bioengineering using nano-scale materials. The objective of this course is to learn the basic principles of each part of the course, and to deepen the understanding of how these principles are connected to practical research and development. Faculty members from AIST of the collaborative graduate school will give lectures on the background and future prospects of cutting-edge technologies.
Expected Learning
Be able to prepare agenda as a student who will be involved with life science, biotechnology research in future.
Course schedule
Week 1(4/ 7):Introduction Chikashi Nakamura
Week 2(4/14):Genome Editing 1 Yoshio Kato
Week 3(4/21):Genome Editing 2 Yoshio Kato
Week 4(4/28):Genome Editing 3 Yoshio Kato
Week 5(5/12):Genome Editing 4 Yoshio Kato
Week 6(5/19):Nanobiomechanics 1 Ayana Yamagishi
Week 7(5/26):Nanobiomechanics 2 Ayana Yamagishi
Week 8(6/ 2):Nanobiomaterials 1 Hyonchol Kim
Week 9(6/ 9):Nanobiomaterials 2 Hyonchol Kim
Week10(6/16):Nanobiomaterials 3 Hyonchol Kim
Week11(6/23):Nanobiomaterials 4 Hyonchol Kim
Week12(6/30):Nanobiologistics 1 Chikashi Nakamura
Week13(7/ 7):Nanobiologistics 2 Chikashi Nakamura
Week14(7/14):Nanobiosensing 1 Chikashi Nakamura
Week15(7/21):Nanobiosensing 2 Chikashi Nakamura


Week1:The outline of the lecture will be explained in the first guidance.
Week2-5:Genome Editing 1-4, Dr. Kato will intoroduce genome editing protein and nucleic acid chemistry, which are attracting attention as a nanobioengineering technology that can freely manipulate genome sequece.
Week6-7:Nanobiomechanics 1-2, Dr. Yamagishi will discuss the mechanical functions of the cytoskeleton and the mechanism by which intermediate filament nestin is involved in the mechanical properties of cancer cells.
Week8-11: Nanobiomaterials 1-4, Dr. Kim will explain the application of nanomaterials for the evaluation of properties of target biomolecules and cells. In addition, principles of various microscopic techniques, which are basis of the applications, will be explained.
Week12-13:Nanobiologistics 1-2, Dr. Nakamura will provide an overview of related technologies, focusing on molecular transport to cells, and introduce examples of the latest technological developments.
Week14-15:Nanobiosensing 1-2, Dr. Nakamura will discuss intracellular measurement technology using nanoscale materials, especially the technology using nanoneedles.
The aim is to understand the direction of biotechnology throughout this lecture.
The theme of the report will be presented in the 12th lecture and collected in the 15th lecture.
Prerequisites
None
Required Text(s) and Materials
None
References
Molecular Biology of the Cell
Watson Molecular Biology of the Gene, James D. Watson
Assessment/Grading
Contribution to the lectures:50%(Mini-exam, Practice), Report:50% (Theme of report will be informed in the 12th Lecture and dead line of report submission is the 15th lecture.)
Message from instructor(s)
・No conditions for this course. Students who are interested in advanced research will be welcomed.
・Attendance will be counted by mini-exam or call over at each lecuture.
・Any questions will be welcomed during or after the lecutre, or you can come to office during the following office hour, or by e-mail.
Course keywords
Cell Engineering,Genome Editing,Biosensor,Nanobiotechnology
Office hours
Every Monday, Friday, 10:00〜17:00 Office:Room404, Bldg11
Remarks 1
Remarks 2
Related URL
https://staff.aist.go.jp/chikashi-nakamura/en/index.html
Lecture Language
Japanese
Language Subject
Last update
3/5/2021 3:31:09 PM