Course title
食料安全科学特論II   [Safe food production Science II]
Course category courses for the 5-years doctral program  Requirement   Credit 1 
Department   Year   Semester 3rd 
Course type 3rd  Course code 231014
Instructor(s)
佐藤 令一   [SATO Ryoichi]
Facility affiliation Graduate School of Bio-Applications and Systems Engineering Office afjgxte/L1151  Email address

Course description
We will study in detail about Bt insecticidal proteins which are produced by a soil bacterium, Bacillus thuringiensis to understand whether they are really safe or not, since they have been being used as organic insecticides or gene sources for gene modified products. We will also study about insect defense mechanisms against microorganisms.
Expected Learning
Gene modified food (GMF) is a subject of interdiciplinaly region which is involved in diploma policy of our department. However, to establish own opinion regarding the safety and benefit, students must study basic nowledge on BT insecticidal protein. Consequently,students study molecular biological aspects of BT in insecticidal protein. Also, student study about insect defense mechanism against microoganisms.
Course schedule
1. Molecular biological aspects of Domain I of Bt insecticidal protein.
2. Molecular biological aspects of Domain II of Bt insecticidal protein.
3. Molecular biological aspects of Domain III of Bt insecticidal protein.
4. Mode of action of Bt insecticidal protein against insect midgut cells.
5. Microorganisms-recogtion system of the insect immunity.
6. Role of C-type lectins in a cell immunity, nodule formatin system.
7. Molecules and mechanism for the nodule formatin.
8. Final presentation

Prerequisites
Required Text(s) and Materials
No text
References
Mode of action of Bt: DOI, 10.3390/toxins11020124
Assessment/Grading
Result of test which is carried out in every class will be evaluated. Understanding of molecular biological aspects of BT insecticidal protein and basic knowledge of the systems for insect immunity will be appreciated.
Message from instructor(s)
Course keywords
Office hours
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
1/14/2021 12:28:16 PM