Course title
蛋白質・核酸科学   [Protein and Nucleotide Science]
Course category	technology speciality courses	Requirement		Credit	1
Department		Year	2～4	Semester	3rd
Course type	3rd	Course code	022169
Instructor(s)
池袋 一典, 津川 若子, 黒田 裕   [IKEBUKURO Kazunori, TSUGAWA Wakako, KURODA Yutaka]
Facility affiliation	Faculty of Engineering	Office		Email address

Course description

Fundamental knowledge of relationship between the structure and function of protein will be explained. We also teache basic knowledge of the protein engineering especially, site directed mutagenesis . The application of the enzymes and proteins will be introduced. Google class code is "ev342i6".

Expected Learning

The students will know the relationship between the structure and funciton of proteins and how we can analysis and improve those fuctions with protein engineering. Commercialization is also very important process for the studetns in Dept. Engineering, so we will introduce those successful examples.

Course schedule

The following issues will be lectured. 1. Fundamental understanding of the structure of ptoteins as polypeptides. 2. Fundamental methodologies for the analyses of protein structures. 3. The methodology for comparison of protein structures. 4. The methodology for structural prediction of proteins. 5. The methodology for prediction of interactions of proteins. 6. How to transform the E. coli with the target gene. 7. How to produce target proteins in E. coli. 8. How to change amino acid of the target protein (site directed mutagensis). 9. Nucleic acid engineering. 10. Aptamer 11. Commercially available enzymes. 12. The problems in commecialization of proteins.

Prerequisites

To better understanding, it is recommended to take the lecture of "Basic phycics", "Basic Chemistry" and "Basic biology". This is a part of learning the course of Biochemistry and Molecular biology.

Required Text(s) and Materials

Introduction of protein science, edited by Fumio Arisaka, Shokabo.

References

Assessment/Grading

This course is divided three parts, and in each of them, exam of report will be conducted and the grade is assessed considering the those three parts.

Message from instructor(s)

We will introduce the cutting edge reasearches and those are of course written in English. So the English reading is required for this lecture.

Course keywords

Office hours

Driday, 12-13 o'clock.

Remarks 1

Remarks 2

Related URL

https://classroom.google.com/c/NTAxODA3MzI2MDAz

Lecture Language

Japanese

Language Subject

Last update

9/28/2022 12:52:55 PM