| Course title | |||||
| 機器分析Ⅰ [Instrumental AnalysisⅠ] | |||||
| Course category | technology speciality courses | Requirement | Credit | 2 | |
| Department | Year | 2～4 | Semester | 3rd | |
| Course type | 3rd | Course code | 022384 | ||
| Instructor(s) | |||||
| 岡本 昭子, 加納 太一 [OKAMOTO Akiko, KANO Taichi] | |||||
| Facility affiliation | Faculty of Engineering | Office | Email address | ||
| Course description |
|
This lecture will aim to understand the basics of various instrumental analysis methods necessary for analyzing and evaluating organic compounds and polymer materials, especially the basic principles. Analytical methods for organic compounds include (1) mass spectrometry, (2) infrared spectroscopy, (3) proton nuclear magnetic resonance spectroscopy, and (4) carbon-13 nuclear magnetic resonance spectroscopy, which are indispensable means for molecular structure analysis in recent years. In response to the great development of structural and material information analysis technology, in actual research and development after graduation research, ⑤ X-ray crystal structure analysis, ⑥ chromatography, ⑦ thermal analysis, etc. are used. Multifaceted analysis and organization based on material information will be required.In this lecture, by understanding the basic analysis principles of organic compounds and polymer materials and learning practical analysis examples, you will acquire a bird's-eye view of basic analysis and analysis of organic compounds and polymer materials. The lecture will be divided into the first half and the second half. In the first half, you will learn a wide range of subjects such as (1), (2), (5) to (7) spectroscopic analysis, separation analysis, and thermal analysis. In the latter half, as a practical structural analysis of organic compounds, we will rationally identify the structures of various organic molecules based on the spectral analysis that combines (1) to (4), with particular emphasis on (3) proton nuclear magnetic resonance spectroscopy. Develop practical skills. Improve the ability to determine the structure of organic molecules and macromolecules based on the contents learned in Organic Chemistry I to III. This subject is classified into "specialized subject II" of "specialized subject" in the curriculum of the Department of Applied Chemistry. |
| Expected Learning |
| The students should understand basics of the above mentioned spectroscopic analyses and cultivate practical ability to identify the structure of organic molecules based on rational and integrated analysis of the spectroscopic methods involving (1) mass spectrometry, (2) infrared spectroscopy, (3) proton nuclear magnetic resonance spectroscopy, (4) carbon-13 nuclear magnetic resonance spectroscopy, (5) X-ray crystal structure analysis, (6) chromatography, and (7) thermal analysis. To acquire the ability to integrate the obtained information and determine the structure of organic molecules with typical structures. Diploma Policy Perspective: See the curriculum map for course guidance. |
| Course schedule |
|
Session 1: Introduction and Infrared spectroscopy (1) Session 2: X-ray-crystallography (1) Session 3: X-ray-crystallography (2) Session 4: Infrared spectroscopy (2) Session 5: Mass spectrometry (1) Session 6: Mass spectrometry (2) and Chromatography (1) [GC] Session 7: Chromatography (2) [HPLC, GC, and TLC] and Thermal analysis [TG-DTA and DSC] Session 8: Midterm Examination Session 9: Proton nuclear-magnetic-resonance spectroscopic method (1) Session 10: Proton nuclear-magnetic-resonance spectroscopic method (2) Session 11: Proton nuclear-magnetic-resonance spectroscopic method (3) Session 12: Proton nuclear-magnetic-resonance spectroscopic method (4) Session 13: Carbon-13 nuclear magnetic resonance spectroscopic method (1) Session 14: Carbon-13 nuclear magnetic resonance spectroscopic method (2) Session 15: Final Examination |
| Prerequisites |
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Organic Chemistry I-III have been learn completely . It is divided into specialized subjects. In addition to the 30 hours of class hours, refer to textbooks and reference books to prepare and review according to the standard number of hours of the university. |
| Required Text(s) and Materials |
|
1) Instrumental Methods in Analytical Chemstry by Hisanori Imura & Teruo Hinoue, Kagaku Dojin. ISBN: 978-4-7598-1808-6 [lecture 1-8] 2) Spectroscopic Methods in Organic Chemistry by M. Hesse, H. Meier, B. Zeeh Kagaku Dojin, ISBN: 978-4-7598-1193-3 [lecture 9-15] 3) Organic Chemistry (the 8 the edition) by John McMurry (1/3) Tokyo Kagaku Dojin, ISBN: 978-4-8079-0809-7 [lecture 9-15] The three text books are required when you attend the first lecture. |
| References |
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1) Identification method (the 7th edition) by the spectrum of an organic compound, Tokyo Kagaku Dojin, ISBN: 4-8079-0633-X 2) Spectroscopic analysis of organic compounds Tokyo Kagaku Dojin, ISBN: 978-4-8079-0725-0 3) Spectroscopic analysis of organic compounds 1D, 2D NMR/IR/UV/MS Takenori Kusumi, Shokabo, ISBN: 978-4-7853-3509-0 |
| Assessment/Grading |
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Midterm (50%) and Final Exam (50%). For understanding of the students, report and/or mini test may be given and included the assessment. Report: Based on the content of the lectures dealt with in that session, the point of evaluation is to be able to gain insight into the principles and rational explanations leading to compound analysis. The deadline for submission varies depending on the content of the assignment. Follow the announcement of the instructor. Examination: Evaluate the knowledge about the principles and methods of analysis handled in the lecture, the information obtained by the analysis, the understanding of specific cases, and the ability to systematically organize the information and analyze unknown compounds. |
| Message from instructor(s) |
| Structural determination of organic molecules based on spectroscopic analysis is an essential skill for research and development. Though it may seem difficult at the beginning, rational approaches for the structural analysis would be more interesting to the students after working on exercises repeatedly, week by week. This lecture will provide the fundamentals of the spectroscopic analysis useful for the entire field of molecular science. |
| Course keywords |
| Mass spectrometry, infrared spectroscopy, a proton nuclear magnetic resonance spectroscopic method, a carbon-13 nuclear-magnetic-resonance spectroscopic method |
| Office hours |
| Office hours: Bldg.4, 248a room (lecture 1-8); New No. 1 Hall N510B room (lecture 9-15); Please contact the teacher before your visiting. |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/23/2022 1:38:59 PM |