Course title
ナノバイオエンジニアリング   [Nanobioengineering]
Course category	technology speciality courses	Requirement		Credit	1
Department		Year	3～4	Semester	1st
Course type	1st	Course code	023158
Instructor(s)
中村 史, 金 賢徹   [NAKAMURA Chikashi, KIM Hyonchol]
Facility affiliation	Graduate School of Engineering	Office	3158	Email address

Course description

Google Classroom's Classcode lll4nrq In this lecture, you will study the most advanced research related to bioengineering that is actually being conducted in the department of lifescience and Biotechnology (https://www.aist.go.jp/aist_e/dept/en_dlsbt.html) of the National Institute of Advanced Industrial Science and Technology (AIST), especially research related to nano-bioengineering using nano-scale materials. The objective of this course is to learn the basic principles of each part of the course, and to deepen the understanding of how these principles are connected to practical research and development. Faculty members from AIST of the collaborative graduate school will give lectures on the background and future prospects of cutting-edge technologies.

Expected Learning

Be able to prepare agenda as a student who will be involved with life science, biotechnology research in future.

Course schedule

Week 1（４／１３）：Introduction　Chikashi Nakamura Week 2（４／２０）：Genome Editing 1　Yoshio Kato Week 3（４／２７）：Genome Editing 2　Yoshio Kato Week 4（５／１１）：Genome Editing 3　Yoshio Kato Week 5（５／１８）：Genome Editing 4　Yoshio Kato Week 6（５／２５）：Nanobiomechanics 1　Ayana Yamagishi Week 7（６／　１）：Nanobiomechanics 2　Ayana Yamagishi Week 8（６／　８）：Nanobiomechanics 3　Ayana Yamagishi Week 9（６／１５）：Nanobiomechanics 4　Ayana Yamagishi Week10（６／２２）：Nanobiomaterials 1 Hyonchol Kim Week11（６／２９）：Nanobiomaterials 2 Hyonchol Kim Week12（７／　６）：Nanobiosensing 1　Chikashi Nakamura Week13（７／１３）：Nanobiosensing 2　Chikashi Nakamura Week14（７／２０）：Nanobiosensing 3　Chikashi Nakamura Week15（７／２７）：Nanobiosensing 4　Chikashi Nakamura Week1:The outline of the lecture will be explained in the first guidance. Week2-5：Genome Editing 1-4, Dr. Kato will intoroduce genome editing protein and nucleic acid chemistry, which are attracting attention as a nanobioengineering technology that can freely manipulate genome sequece. Week6-9：Nanobiomechanics 1-4, Dr. Yamagishi will discuss the structure of the cytoskeleton and its role in cell motility and adhesion. Especially, the mechanism by which intermediate filaments and mechano sensitive channels are involved in the mechanical properties of cancer cells will be discuss. Week10,11: Nanobiomaterials 1,2, Dr. Kim will explain the application of nanomaterials for the evaluation of properties of target biomolecules and cells. In addition, principles of various microscopic techniques, which are basis of the applications, will be explained. Week12-15：Nanobiosensing 1-4, Dr. Nakamura will discuss intracellular measurement technology using nanoscale materials, especially the technology using nanoneedles. The aim is to understand the direction of biotechnology throughout this lecture.

Prerequisites

None

Required Text(s) and Materials

None

References

Molecular Biology of the Cell Watson Molecular Biology of the Gene, James D. Watson

Assessment/Grading

Contribution to the lectures:50%（Mini-exam, Practice), Report:50% (Theme of report will be informed in the 12th Lecture and dead line of report submission is the 15th lecture.）

Message from instructor(s)

・No conditions for this course. Students who are interested in advanced research will be welcomed. ・Attendance will be counted by mini-exam or call over at each lecuture. ・Any questions will be welcomed during or after the lecutre, or you can come to office during the following office hour, or by e-mail.

Course keywords

Cell Engineering，Genome Editing，Biosensor，Nanobiotechnology

Office hours

Every Monday, Friday, 10:00〜17:00 Office：Room404, Bldg11

Remarks 1

Remarks 2

Related URL

https://staff.aist.go.jp/chikashi-nakamura/en/index.html

Lecture Language

Japanese

Language Subject

Last update

4/12/2022 2:32:43 PM