| Course title | |||||
| 生命科学特論Ⅱ [Life science special lectureⅡ] | |||||
| Course category | courses for the doctral program | Requirement | Credit | 2 | |
| Department | Year | ～ | Semester | 3rd | |
| Course type | 3rd | Course code | 148310 | ||
| Instructor(s) | |||||
| 西河 淳 [NISHIKAWA Atsushi] | |||||
| Facility affiliation | Faculty of Agriculture | Office | Email address | ||
| Course description |
|
This lecture is designed to give students advanced knowledge and skills in the field of applied biochemistry by learning the latest knowledge and technology in agriculture. In particular, this lecture is to provide students with the knowledge needed to understand the latest outcomes of glycobiology in the field of applied biochemistry. |
| Expected Learning |
|
Understanding the latest knowledge of glycobiology. Corresponding criteria in the Diploma Policy: (A) and (D)． |
| Course schedule |
|
Many glycoproteins can be found in organisms, and “glycochains”, that are polymers composed of various sugars, bind to the glycoproteins. The glycochain has been elucidated in recent years as its third chain next to proteins and nucleic acids, and the functions have been clarified in various stages such as development, differentiation, proliferation, and canceration. This lecture provides outline of the physiological functions of glycochains, including the role in glycoproteins that have recently been used as "drugs". 1）Concepts of glycobiology 2）What is sugar 3）Structual basis of glycan diversity 4) Cellular organization of glycosylation 5) Biological roles of glycans 6) N-Glycan 7) O-Glycan 8) Glycolipids 9) Glycans in biology 10) Glycans in glycoprotein quality control 11) Bacterial and viral infections 12) Genetic disorders of glycan degradation 13) Genetic disorders of glycosylation 14) Glycosylation change in cancer 15) Glycans in biotechnology and the pharmaceutical industry |
| Prerequisites |
| Students need to preview and review for an amount of time as indicated in the student guidelines of TUAT, in addition to the attendance of lecture. |
| Required Text(s) and Materials |
| References |
| Essentials of glycobiology （Cold spring harbor laboratory press） |
| Assessment/Grading |
| Presentation (50%), and oral examination (50%). |
| Message from instructor(s) |
| Course keywords |
| glycobiology、glycoprotein、carbohydrate、disease |
| Office hours |
| Questions are accepted at the end of the lecture． |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 3/5/2022 12:53:11 PM |