Course title
持続可能な開発のための教育(ESD)   [Education for Sustainable development(ESD)]
Course category specialized courses/ major subjects  Requirement   Credit 1 
Department   Year 34  Semester Fall 
Course type Fall  Course code 02l3157
Instructor(s)
斎藤 広隆   [SAITO Hirotaka]
Facility affiliation Faculty of Agriculture Office   Email address

Course description
In cell regenerative technology, students learn about techniques to realize regenerative induction therapy including cell transplantation therapy. Cell regenerative technology is an applied subject of the special field of biotechnology, and it is a specialized subject of life science. The purpose of this lecture is to understand the latest research content concerning various transplantation.
We learn about the basis of cell regeneration and latest research contents related to various transplantation. Students are encouraged to study using data provided in the class to build a systematic understanding on the cell regenerative technology.

Biomedical cell engineering
In the field of biomedical cell engineering, we introduce examples of restoring cellular functions by targeting mitochondria and implementing modifications and transplants (mitochondrial engineering). Mitochondria are cellular organelles associated with many diseases, and various techniques used in bioengineering are utilized for their application. From the perspective of bioengineering, we will explain how to utilize mitochondria.Mitochondria have been implicated in a wide range of diseases, including cancer, neurodegenerative diseases, oxidative stress, ischemia-reperfusion injury (damage that occurs after blood flow is restored following organ transplantation or myocardial infarction), immunity, and inflammation. We will present examples that focus on mitochondria to understand how to suppress cellular abnormalities observed in these diseases. In addition, we will consider the novel approach of organelle transplantation.

class code : m3ujfj6
Expected Learning
The standard of this lecture is to understand the contents and problems of latest research on cell regenerative technology.
This subject is associated with the corresponding criteria B, C in the Diploma Policy.
Course schedule
1. General remarks on cell regenerative technology
2. Basic of cell regenerative technology (1) transformant technology
3. Undifferentiated control of stem cells
4. Hematopoietic stem cell transplantation
5. Cloned animals, epigenetic
6. Application of iPS cells
7. Cartilage regeneration
8. Hair root regeneration
9. Introduction to Biomedical cell engineering
10. Electron Transport Chain and Supercomplexes
11. Reactive Oxygen Species and Oxidative Stress
12. Membrane Structure and Fusion-Fission
13. Protein Transport and Mitophagy
14. Mitochondrial Transplantation and Administration Therapy
15. Summary of Cell Bioengineering
Prerequisites
In this lecture, it is desirable to take preliminary or simultaneous course of biology, fundamental biochemistry, basic molecular biology, life science I, II, molecular biology I, II, cell biology I, II, regulatory science.In addition to the above, Biomedical cell engineering should take Physics I-III, Biophysical Chemistry I and II, Instrumental Analysis, and Advanced Instrumental Analysis.
In addition to 30 hours that students spend in the class, students are recommended to prepare for and revise the lectures, spending the standard amount of time as specified by the University and using the lecture handouts as well as the references specified below.
Required Text(s) and Materials
Prints are distributed in the lecture.
References
Introduce during class.
Assessment/Grading
Report (100%)
Message from instructor(s)
I want you to think about what you need for medical care in the future.
Course keywords
Cell regeneration, Transplantation therapy
Office hours
After each lesson, respond as appropriate to questions etc.
Remarks 1
Remarks 2
Related URL
Lecture Language
Japanese
Language Subject
Last update
4/4/2023 2:39:48 PM