| Course title | |||||
| 論理回路 [Logic Circuit] | |||||
| Course category | Requirement | Credit | 1 | ||
| Department | Year | ～ | Semester | YearLong | |
| Course type | YearLong | Course code | 106b0201 | ||
| Instructor(s) | |||||
| 吉田 敏則 [YOSHIDA Toshinori] | |||||
| Facility affiliation | Graduate School of Bio-Applications and Systems Engineering | Office | Email address | ||
| Course description |
| The objective of this course is to explain the function and structure of cells from the viewpoint of mechanical engineering, and to learn about the interrelationship between the mechanical response of cells and the activation of biochemical signals in cells, in order to acquire the latest findings in the interdisciplinary research field leading from cell biomechanics to mechanobiology and methods to analyze and evaluate cell functions from a mechanical viewpoint. |
| Expected Learning |
|
Learners who successfully complete this course will be able to understand the importance of mechanobiology research on cellular force-sensing and response mechanisms, especially by learning how cells in blood vessels sense hemodynamic stimuli, causing the activation of intracellular biochemical signals and ultimately leading to cellular responses. Corresponding criteria in the Diploma Policy: See the Curriculum maps. |
| Course schedule |
|
[1] What is Mechanobiology? [2] Structure of blood vessels and properties of vascular cells 1 [3] Structure of blood vessels and properties of vascular cells 2 [4] Hemodynamic environment and mechanical stimuli to blood vessels [5] Responses of vascular endothelial cells to fluid shear stress [6] Responses of vascular endothelial cells to cyclic stretch [7] Responses of vascular endothelial cells to hydrostatic pressure [8] Summary |
| Prerequisites |
| It is desirable to have studied Biochemistry (or Cell Biology) and Advanced Biomechanics I. |
| Required Text(s) and Materials |
| Handouts to be distributed in the class. |
| References |
| Assessment/Grading |
|
Final report 100% 90% or more: S, 80-89%: A, 70-79%: B, 60-69%: C |
| Message from instructor(s) |
| Course keywords |
| Vascular endothelial cells, Mechanobiology, Shear stress, Cyclic stretch, Hydrostatic pressure |
| Office hours |
| Ask questions after the lecture as much as possible. Ask by email in other cases. |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Japanese |
| Language Subject |
| Last update |
| 2/25/2023 5:35:39 PM |