| Course title | |||||
| 環境科学Ⅱ [Environmental ScienceⅡ] | |||||
| Course category | Requirement | Credit | 0.5 | ||
| Department | Year | ～ | Semester | YearLong | |
| Course type | YearLong | Course code | 96224 | ||
| Instructor(s) | |||||
| 米澤 宣行, 尾池 秀章 [YONEZAWA Noriyuki, OIKE Hideaki] | |||||
| Facility affiliation | Office | Email address | |||
| Course description |
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December 1, 2023 (Fri.) 10:00~ Faculty of Agriculture, Ibaraki University, Kobushi Kaikan 2F, Seminar Room B, Face-to-Face In this lecture, the functions of coenzymes used in metabolism and enzymatic reactions will be explained. This lecture will provide advanced knowledge and skills in the field of applied life sciences. Living organisms produce energies and biomaterials in cells, to maintain their life. The production activities absolutely depend on reactions catalyzed by enzymes. However, some enzymes can not complete the reactions by themselves and require substances called "coenzymes" for the reactions. In this lecture, I will talk about species, functions, and biosynthesis of coenzymes, especially acyl-carrier, CoA, providing the most up-to-date information. |
| Expected Learning |
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・ Ability to explain the relationship between coenzymes and vitamins. ・ Ability to explain the role of coenzymes. ・ Ability to explain the in vivo kinetics of coenzymes. ・ Ability to discuss the application of the coenzyme biosynthetic pathways as a drug target. Please refer to the curriculum map of the course guide for the correspondence between the contents of this lecture and the diploma policy of this course. |
| Course schedule |
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1. Species, structures, and functions of coenzymes (ATP, NAD(P)H, CoA, etc). 2. Biosynthetic pathways of coenzymes (relationship of vitamins and coenzymes). 3. CoA biosynthetic pathway, its regulation mechanisms, and changes of intracellular CoA and its thioesters (bacteria, archaea, and eukarya) 4. Application of coenzyme biosynthetic pathways to drag targets. |
| Prerequisites |
| In addition to the 7.5 hours of class time and the time required to create reports, etc., refer to the distributed lecture materials and reference books, and prepare and review according to the standard number of hours of the university. |
| Required Text(s) and Materials |
| Handouts will be provided in the class. |
| References |
| To be announced in the lecture. |
| Assessment/Grading |
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Class participation attitude: 30% Report: 70% |
| Message from instructor(s) |
| Course keywords |
| coenzyme, vitamin, metabolism, enzyme |
| Office hours |
| Questions will be accepted at the end of lecture and through e-mail after the lecture. shigeru.chohnan.agr[at]vc.ibaraki.ac.jp |
| Remarks 1 |
| Remarks 2 |
| Related URL |
| Lecture Language |
| Language Subject |
| Last update |
| 2/2/2023 3:56:11 PM |